Valerian root (Valeriana officinalis) is a popular and widely available herbal supplement, primarily used to treat insomnia and anxiety. Until recently, its mechanism of action has remained unknown. Neurobiological research has begun to show that the herb, with its active valerenic acid, interacts with the GABA(A)-ergic system, a mechanism of action similar to the benzodiazepine drugs. This ser...

In some medicinal plants a specific plant-fungus association, known as arbuscular mycorrhizal (AM) symbiosis, increases the levels of secondary plant metabolites and/or plant growth. In this study, the effects of three different AM treatments on biomass and sesquiterpenic acid concentrations in two IN VITRO propagated genotypes of valerian ( VALERIANA OFFICINALIS L., Valerianaceae) were investi...

Hot flash is among the most common complaints of menopausal women, affecting their career, social activities and quality of life. This study aimed to investigate the effects of Valerian on hot flashes in menopausal women. In this double blind clinical trial, 68 menopausal women with the chief complaint of hot flash were enrolled using sampling at hand and were randomly divided into drug and pla...

Due to the electrochemical nature of the communication structure of the brain an intimate relationship between neurotransmitter activity on one side and field potentials (EEG) on the other side have been reported. From this it can be assumed that the electrical activity reflects the net effect of drug action. The influence of increasing doses of Ze 91019 on field potentials in chronically instr...

Serious sleep problems are common in children with an intellectual deficit (ID), and are often the source of much distress for both the child and caregivers. As yet, no satisfactory long-term treatment exists for intransigent sleep difficulties in children with an ID. Valerian, Valeriana spp., has been used for thousands of years to induce relaxation and sleep. Scientific investigation of valer...

Title:Valeriana officinalis root extract suppresses physical and psychological stress responses by decreasing the ratio of monoamine neurotransmitters to their metabolites Authors:

background: plant cell cultivations are considered as an alternative to agricultural processes for producing valuable phytochemicals (secondary metabolites). the use of plant cell cultures has overcome several inconveniences for the production of secondary metabolites. objective: the essential oils isolated from roots of 24-month-old field grown valerian (valeriana sisymbriifolium) and hairy ro...

Valeriana officinalis belongs to the Valerianaceae family, is a well-known herb and medicinal plant. Plant roots are commonly used as medicine by pharmaceutical industry. Observation on morpho-agronomic characteristics of valerian propagated in vitro needed determine their morphological production field. The study aimed observe derived from culture. experiment was conducted at Indonesian Spices...

A Valerian is a popular drug among the population. It can be use against anxiety, fear and intension. Our purpose was tu study to what a degree it is included in the practice of the doctors of dental medicine against the stress from the dental treatment. A direct anonymous group inquiry among 296 doctors of dental medicine in the whole country was carried out. From the received information we e...