Network flow problems with non-convex piecewise linear cost structures arise in many application areas, most notably in freight transportation and supply chain management. In the present paper, we consider mixed-integer programming (MIP) formulations of a generic multi-commodity network flow problem with piecewise linear costs. The formulations we study are based on variable disaggregation tech...

In this paper we intend to improve the explanatory power of regressions when the deletion method is used for the remedy of Multicolinearity. If one deletes the variable (s) that is (are) responsible for Multicolinearity, he loses some information that is not common between the deleted variable (s) and the other remaining variables in the regression. To improve this method, we run the deleted va...

BACKGROUND The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) received five years' funding ($21 112 866) from the National Institutes of Health to compare carotid stenting to surgery for stroke prevention in 2500 randomized participants at 40 sites. AIMS Herein we evaluate the change in the CREST budget from a fixed to variable-cost model and recommend strategies for t...

A strategy that integrates an organization's marketing goals into a cohesive whole, ideally drawn from market research, focuses on the ideal product mix in order to achieve maximum profit potential; the marketing strategy is set out as a marketing plan, a good idea, method, information, object, or service that is the end result of a process and serves as a need or want satisfier. It is usually ...