The systemic vasculitides (SV) are a heterogeneous group of rare affections, characterized by a primary process of inflammation and damage of the vessel wall, resulting in blood flow impairment and, ultimately, in ischemia of the distal tissues. Pulmonary vasculitis usually is a component of a systemic small vessel vasculitis. Pulmonary vasculitides can be classified into three major groups: a)...

churg-strauss syndrome (css) is a granulomatous small vessel vasculitis . it is characterized by asthma, allergic granulomatosis and vasculitis . this syndrome is rare in children. a 5 years old boy was admitted with cough, fever and dyspnea for 2 weeks. on the basis of  laboratory data (peripheral eosinophilia), associated with skin biopsy, and history of css in his sister, this disease was ev...

We review the terminology used in the context of cutaneous vasculitis with discussion of cutaneous leukocytoclastic vasculitis, its clinical approach, differential diagnosis and treatment algorithm. Cutaneous vasculitis encompasses a wide spectrum of conditions of very different severity and urgency, from limited skin disease to severe systemic life-threatening vasculitis. This review will empo...

OBJECTIVES (a) To assess plasma fibrinolytic parameters in patients with rheumatoid arthritis (RA) and to determine whether there are differences between patients with RA alone and those with RA complicated by vasculitis. (b) To determine if patients with RA respond differently to venous occlusion compared with normal subjects and to assess whether such a response differs in patients with RA al...

Localized gastrointestinal vasculitis is a rare condition. It may be observed as an incidental unexpected pathologic finding at the time of biopsy of an abdominal mass or may present as unexplained abdominal pain with or without unexplained lower gastrointestinal bleeding. In this report we describe a new case of localized polyarteritis nodosa with involvement of peripancreatic middle-sized blo...

BACKGROUND Cutaneous vasculitis has been mainly associated with hematologic cancer. The association of solid neoplasms with cutaneous paraneoplastic vasculitis is rare. We report a case of cutaneous leucocytoclastic vasculitis that revealed a gastric adenocarcinoma. CASE REPORT A 72-year-old man presented with an acute diffuse polymorphic eruption, with erythematous, vesicular, and necrotic l...

OBJECTIVE To assess the expression of ICAM1, VCAM1, E-selectin, CD44, and TNF alpha in labial salivary glands of patients with rheumatoid vasculitis. METHODS Labial salivary glands from six patients with rheumatoid vasculitis before and after treatment, six aged matched rheumatoid arthritis patients without clinical evidence of rheumatoid vasculitis, 10 patients with primary Sjögren syndrome,...

The primary vasculitides constitute a heterogeneous group of immune mediated diseases incompletely understood pathogenesis currently classified by the size blood vessels affected (Chapel Hill classification). In recent years, several drugs with well-characterized immunological targets have been tested in clinical trials large vessel vasculitis and small vasculitis. Such provide reverse translat...