Purpose Previous articles in this supplement described rationale for and development of the pause marker (PM), a diagnostic marker of childhood apraxia of speech (CAS), and studies supporting its validity and reliability. The present article assesses the theoretical coherence of the PM with speech processing deficits in CAS. Method PM and other scores were obtained for 264 participants in 6 g...

Ultrasound imaging is an adjunct to traditional speech therapy that has shown to be beneficial in the remediation of speech sound errors. Ultrasound biofeedback can be utilized during therapy to provide clients with additional knowledge about their tongue shapes when attempting to produce sounds that are erroneous. The additional feedback may assist children with childhood apraxia of speech (CA...

We report clinical, cytogenetic, and comparative genomic hybridization findings for three siblings with an unbalanced 4q;16q translocation, minor malformations, and cognitive abnormalities, including childhood apraxia of speech, a rare, severe motor speech disorder. Breakpoint findings indicate that in addition to possible contributions from duplicated genes on chromosome 16, haploinsufficiency...

Childhood apraxia of speech (CAS) is a pediatric motor speech disorder characterized by poor motor planning/programming skills (ASHA, 2007). Treatment of CAS focuses on improving motoric processes for speech production. One important consideration within the therapeutic context is the complexity of speech targets. While many studies have examined complexity across linguistic domains (Gierut, 20...

Corticobasal ganglionic degeneration (CBGD) is a progressive neurological disorder characterized by gradual nerve cell loss and atrophy of the cerebral cortex and basal ganglia. Symptoms of the disorder include verbal apraxia and language disturbances along with bradykinesia and rigidity. There have been no reports to date of acquired or neurogenic stuttering associated with CBGD. We describe a...

The term “aphemia” is now used to describe a motor disorder that affects speech production but leaves the comprehension of spoken and written language intact. Aphemia is a specific form of mutism. Aphemia was formerly referred to as phonetic disintegration, pure anarthria, apraxic dysarthria, cortical dysarthria, verbal apraxia, subcortical motor aphasia, pure motor aphasia, small or mini Broca...

UNLABELLED Forty-two children (29 boys and 13 girls), ages 3-10 years, were referred from the caseloads of clinical speech-language pathologists for suspected childhood apraxia of speech (CAS). According to results from tests of speech and oral motor skills, 22 children met criteria for CAS, including a severely limited consonant and vowel repertoire, difficulty sequencing syllables, and incons...

The FOXP2 gene, located on human 7q31 (at the SPCH1 locus), encodes a transcription factor containing a polyglutamine tract and a forkhead domain. FOXP2 is mutated in a severe monogenic form of speech and language impairment, segregating within a single large pedigree, and is also disrupted by a translocation in an isolated case. Several studies of autistic disorder have demonstrated linkage to...