Antimicrobial activities of the leaf extracts of Cymbopogon citatrus (lemongrass) and Vernonia amygdalina (bitter leaf) and the seed extracts of Garcinia kola (bitter kola) were carried out. G. kola had effect only on Staphylococcus aureus and Escherichia coli with no inhibition on Candida albicans. Ethanol, cold water and hot water extracts of Vernonia amygdalina and Cymbopogon citratus showed...

Nothovernoniagen. nov., is described as a new genus for the tropical African Vernonia purpurea Sch.Bip. ex Walp. and Vernonia amblyolepis Bak, having cymiform inflorescences, pedunculate heads with differentiated foliiform bracts at the base, apiculate involucral bracts with scarious lateral margins, spiculiferous corolla lobes, and strongly spinose, sublopohate tricolporate pollen with the col...

Antipyretic effect of petroleum ether and chloroform soluble fractions of ethanol extract of the roots of Vernonia cinerea was investigated. Intraperitoneal administration of boiled milk at a dose 0.5 ml/kg body weight in albino rabbit leads to pyrexia. Intraperitoneal (i.p. route) administration of petroleum ether and chloroform soluble fractions of ethanol extract of the roots of Vernonia cin...

Background: Some locally available plant foods in Nigeria have received attention as dietary agents that modulate gastrointestinal functions and carbohydrate metabolism. Objective: The effect of some of these plant foods like Detarium microcarpium (legume) and Vernonia amygdalina (vegetable) on postprandial glucose response of healthy non-diabetic adults was investigated. These two studies were...

This study investigated the antidiabetic activity of the various combinations (ratios) of metformin (50 mg/kg) and aqueous extracts of the leaves of Vernonia amygdalina (100 mg/kg). The ratios of Extract to Metformin were 1:1, 2 1, and 2:1 and distilled water (control, p.o.) were given to both normoglycemic and alloxan-induced diabetic Wister albino rats. Blood was withdrawn and tested at 0, 1,...

The spread of multi-drug resistant tuberculosis necessitates the discovery of new classes of antibacterials and compounds that inhibit macromolecules involved in these resistant mechanisms. Thirty ethanol extracts from nineteen selected plants from Zimbabwe were screened against Mycobacterium aurum and Corynebacterium glutamicum using the agar disk diffusion method. These two organisms were use...

objective: vernonia amygdalina (v.  amygdalina) leaf is locally employed in the southern region of nigeria in the treatment of malari a infection. this study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of v.  amygdalina leaf. materials and methods: the active principles of the dried leaf were extracted with ethanol. for quality validation, ch...

Sub-acute Toxicity of Aqueous Extracts of Tephrosia vogelii, Vernonia amygdalina and Senna occidentalis in Rats Immaculate Nabukenya1*, Chris Rubaire-Akiiki1, Denis Mugizi1, John Kateregga1, Deogracious Olila1 and Johan Höglund2 1College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, P.O. Box 7062, Kampala, Uganda 2Department of Biomedical Sciences and Veterinary...

BACKGROUND The emergence and spread of Plasmodium falciparum with resistance to chloroquine (CQ), the safest and cheapest antimalarial drug coupled with the increasing cost of alternative drugs especially in developing countries have necessitated the need to optimize antimalarial actions of plant extracts and restore chloroquine efficacy. OBJECTIVE The present study determines the ability of ...

Recently, considerable attention has been focused on dietary and medicinal phytochemicals that inhibit, reverse or retard diseases caused by oxidative and inflammatory processes. Vernonia amygdalina is a perennial herb belonging to the Asteraceae family. Extracts of the plant have been used in various folk medicines as remedies against helminthic, protozoal and bacterial infections with scienti...