STUDY DESIGN Case control study. PURPOSE To examine the effect of spino-pelvic sagittal parameters and back muscles on osteoporotic vertebral fracture. OVERVIEW OF LITERATURE Low bone mass is not the only important component of the risk on osteoporotic vertebral fracture; many other risk factors also contribute to skeletal fragility. METHODS Seventy-two patients who had a lateral radiogra...

Background: Thalassemia/haemoglobinopathy is a hereditary disease with increased erythropoiesis and expansion of the bone marrow cavity. Consequently, there is a reduction in trabecular bone tissue resulting in osteopenia/osteoporosis. The present study was performed to determine bone mineral density (BMD) in children and adolescents with major thalassemia and its correlation with serum fer...

Symptomatic vertebral fractures are associated with significant morbidity, excess mortality and health and social service expenditure. Up to 20% of patients with an incident vertebral fracture experience a further vertebral fracture within one year. It is therefore important that vertebral fractures are detected early, and treatment considered as soon as possible. Only a third of vertebral frac...

Osteoporosis is a common metabolic skeletal disorder characterized by decreased bone mass and deteriorated bone structure, leading to increased susceptibility to fractures. With aging population, osteoporotic fractures are of global health and socioeconomic importance. The three-dimensional microstructural information of the common osteoporosis-related fracture sites, including vertebra, femora...

Childhood osteoporosis can be treated with intravenous bisphosphonates in order to improve bone mass and density. The aims of this study were to evaluatethe safety and efficacy of six-monthly zoledronic acid (ZA) in children with osteoporosis. A retrospective cohort study of 27 patients (16 males and 11 females) weretreated with six-monthly ZA (0.05mg/kg/dose) for a minimum of one year.17 patie...

Percutaneous vertebral augmentation (VA) and reconstruction with intravertebral polyethylene mesh sac (OptiMesh) and morcelized bone graft provided a minimally invasive efficacious and controlled delivery mechanism to stabilize and treat painful osteoporotic, traumatic and neoplastic vertebral compression fractures (VCFs), as well as avoided serious complications from Polymethylmethacrylate (PM...

BACKGROUND The study was aimed at the development of parameters that could be used as predictors of vertebral strength. Proposed parameters describing vertebral geometry and/or shape can be established on the basis of routine spine roentgenograms, making roentgenography a novel tool for vertebral fracture risk assessment in the future. MATERIAL/METHODS 20 human cadaveric L3 vertebrae were inc...

OBJECTIVES To determine the prevalence of vertebral fracture in postmenopausal women with steroid treated rheumatoid arthritis (RA), and whether the risk of vertebral fracture could be predicted from measurements of bone mineral density (BMD). METHODS Vertebral deformities were defined from spine radiographs in 76 postmenopausal women with steroid treated RA (aged 50-79 years) and 347 age mat...

Purpose/Introduction: To prospectively investigate the relationship among vertebral marrow fat content,marrow apparent diffusion coefficient(ADC),and bone mineral densities(BMD) documented with dual x-ray absorptiometry (DXA) in postmenopausal women. Subjects and Methods: Institutional study approval and informed consent were obtained. Sixty postmenopausal women (mean, 61.7±4.9 years;range, 55-...

BACKGROUND This study compared the role and timing of bone scintigraphy and magnetic resonance imaging (MRI) in the evaluation of vertebral compression fractures (VCFs), before treatment with vertebroplasty and kyphoplasty. To our knowledge, no prior articles have described, in osteoporotic and pathological vertebral fractures, the role of MRI and bone scintigraphy as pre-procedural work up in ...