with significant improve in health-care and treatment of infectious diseases, genetic disorders have created a new era of notification. changes in social attitude towards family life and tendency of parents for limited number of children, sense of responsibility of parents for mental and physical healthiness of children along with their education, needed a new strategy. since most genetic disor...

The chorionic villi of term placentas were examined for A and B blood group substance using the IF technique with heterologous and homologous antisera. No specific fluorescence was found in either the villous trophoblast or vessels of the chorionic villi. The implications of these findings in relation to the question of trophoblastic antigenicity are discussed.

We aimed to investigate the expression of suppressors cytokine signaling (SOCS)-3, transforming growth factor (TGF)-β and indoleamine 2,3-dioxygense (IDO) and to analyse the relationship of SOCS3 and TGF-β with IDO expression in early pregnancy chorionic villi and decidua in the maternal-fetal interface. Western blot analysis and immunohistochemical method were used to detect the expression of ...

The global gene expression profiles of the decidua and chorionic villi of early human pregnancies were analysed by using cDNA microarray technology. Decidual and villous placental tissues were obtained from first trimester abortus and mRNA was extracted for cDNA microarray analysis. The human cDNA microarray [9600 clones, including known regulatory genes and expressed sequence tags (EST)] with ...

The histogenesis of the mouse jejunal mucosa and distribution of cells capable of proliferation were studied by scanning and transmission electron microscopy and light microscopic autoradiography using 3H-thymidine. Villous primordia were found to commence their development as mucosal ridges on day 15 of gestation. Individual villi are identifiable on day 16 of gestation. Some villi reach their...

The chorionic villi in the placenta are responsible for the regulation of fetal oxygen and nutrient transport. Although the peripheral renin-angiotensin system is activated during normal pregnancy, the regulation of the local chorionic villi renin-angiotensin system remains unknown. Therefore, placental chorionic villous tissue was collected from nulliparous third-trimester normotensive or pree...

Mucinous colorectal cancers exhibit a characteristic set of molecular genetic alterations and may be derived from progenitor cells committed to the goblet cell lineage. Previously, we demonstrated that the MUC2 mucin gene promoter drives transgene reporter expression with high specificity in small intestinal goblet cells of transgenic mice. On the basis of these experiments, we reasoned that th...

The increase of sucrase activity in homogenates of jejunum and ileum of suckling rats after cortisone administration has been investigated. Serial tissue sections of villi and crypts were also assayed for sucrase activity and these results were compared with the migration of cells labelled with [(3)H]thymidine along the villus. By using a low dose of cortisone (0.5mg/day per 100g body wt.) it w...

Jejunal villi of chickens generally maintained their structural integrity regardless of the severity of infection with Eimeria necatrix. Only during the severest infection was villar height reduced to a value below measurements of uninoculated controls. Subvillar thickness increased with severity of infection, possibly because of the increasing numbers of parasites present in the host tissue. M...