there is increasing trend in using recombinant stem cells as novel therapeutic candidates in different diseases. these studies encompass different applications from targeted homing of mesenchymal stromal (stem) cells (msc), to arming them with different cytokines. resistance to transfection or transduction methods had urged researchers to look for better gene delivery alternates and optimizing ...

Non-viral delivery systems usually include mechanical, electrical, and chemical methods. Cationic liposomes and cationic polymers are two typical classes of non-viral vectors. Com‐ pared with viral vectors, non-viral ones are considered promising vehicles for gene therapy because of their low toxicity, biocompatibility, and controllability [1, 2], although their low efficacy limits their applic...

objectives : this study sought to assess the effect of low-level laser (lll) on pain and trismus after impacted mandibular third molar surgery. materials and methods : this double blind controlled clinical trial was conducted on 40 healthy patients with no underlying disease and impacted mesioangular mandibular third molars with the same level of difficulty. the patients were divided into two g...

There is increasing trend in using recombinant stem cells as novel therapeutic candidates in different diseases. These studies encompass different applications from targeted homing of Mesenchymal Stromal (stem) Cells (MSC), to arming them with different cytokines. Resistance to transfection or transduction methods had urged researchers to look for better gene delivery alternates and optimizing ...

1. Abstract 2. Introduction 3. Viral vectors 3.1. Adenoviral vectors 3.2. Adeno-associatedvectors 3.3. Retroand Lentiviral vectors 3.4. Herpes viral vectors 4. Chemical gene transfer 5. Physical methods for gene delivery 5.1. Ballistic gene delivery 5.2. Micorseeding 5.3. Electroporation 6. Gene regulation 7. Gene silencing and transcriptional factors 8. Clinical trials 9. Perspective 10. Refer...

background and objectives: baculovirus can be used as a vector in gene delivery system. viral envelope of baculovirus would display expressed protein/peptide and it could render as a potential vaccine delivery system. in this regard, the gene coding for a subunit of shiga toxin (stxa) from escherichia coli ( e. coli ) strain was cloned in a baculovirus expression system. stxa subunit has the ab...