The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study (1985-1993) recruited 29,133 Finnish male cigarette smokers, finding that vitamin E supplementation had no overall effect on mortality. The authors of this paper found that the effect of vitamin E on respiratory infections in ATBC Study participants was modified by age, smoking, and dietary vitamin C intake; therefore, they exam...

A study was conducted to determine the effects of dietary vitamin C on growth performance, feed utilization and carcass biochemical composition of Barbus sharpeyi fingerling. Five diets containing (0, 500, 1000, 1500 and 2000 mg kg-1) of ascorbic acid were fed to benni fingerlings (6.96±0.3 g) in triplicate tanks and twice daily for a period of 56 days. The weight gain significantly increase...

BACKGROUND Previous randomized controlled trials (RCTs) have reported inconsistent findings regarding the association between vitamin C supplementation and the risk of cancer. METHODS We performed a meta-analysis of RCTs to investigate the efficacy of vitamin C supplements for prevention of cancer. We searched the PubMed, EMBASE, and Cochrane Library databases in November 2014 using common ke...

BACKGROUND Recent posttrial analysis of a completed randomized trial found an increased risk of prostate cancer among healthy men taking high-dose vitamin E supplements. Trials that examined the effect of vitamin C supplements on cancer risk are few. OBJECTIVE We examined whether vitamin E or vitamin C supplementation affects the risk of cancer events during posttrial follow-up of the Physici...

BACKGROUND Animal experiments have shown a protective effect of vitamin C on the formation of gallstones. Few data in humans suggest an association between reduced vitamin C intake and increased prevalence of gallstone disease. The aim of this study was to assess the possible association of regular vitamin C supplementation with gallstone prevalence. METHODS An observational, population-based...

background: pregnancy is associated with unfavorable metabolic profile, which might in turn result in adverse pregnancy outcomes. the current study was designed to evaluate the effects of calcium plus vitamin d administration on metabolic status and pregnancy outcomes in healthy pregnant women. methods: this randomized double‑blind placebo‑controlled clinical trial was performed among 42 pregna...

Vitamin C ascorbic acid) is a well-known antioxidant that is involved in anxiety, stress, depression, fatigue and mood state in humans. Studies have suggested that oxidative stress may trigger neuropsychological disorders. Antioxidants may play an important therapeutic role in combating the damage caused by oxidative stress in individuals that suffer from anxiety. In this context, it was hypoth...

Although the role of vitamin C in common cold incidence had been studied extensively, the level of vitamin C intake has not been unequivocally shown to affect the incidence of colds. In the present study the six largest vitamin C supplementation (> or = 1 g/d) studies, including over 5000 episodes in all, have been analysed, and it is shown that common cold incidence is not reduced in the vitam...

OBJECTIVE While iron deficiency is regarded as the major cause of nutritional anaemia, changes in vitamins A, B12, C and E, folic acid and riboflavin status have also been linked to its development and control. This paper provides a systematic review of vitamin supplementation trials relating to the control of nutritional anaemia. METHODS A MEDLINE search was used to find reports of vitamin s...

background chronic inflammation is the most important cause of cardiovascular disease in patients undergoing hemodialysis, and vitamin c as a major antioxidant which could be effective to suppress inflammation. objectives this study was performed to evaluate the effect of vitamin c supplementation on c-reactive protein levels in patients undergoing hemodialysis. patients and methods this random...