OBJECTIVES To determine wasting prevalence among infants aged under 6 months and describe the effects of new case definitions based on WHO growth standards. DESIGN Secondary data analysis of demographic and health survey datasets. SETTING 21 developing countries. POPULATION 15 534 infants under 6 months and 147 694 children aged 6 to under 60 months (median 5072 individuals/country, range...

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Growing evidence suggests acute skeletal muscle wasting is a key factor affecting nutritional support and prognosis in critical patients. Previously, plenty of studies of muscle wasting focused on the peripheral pathway, little was known about the central role. We tested the hypothesis whether central inflammatory pathway and neuropeptides were involved in the process. In lipopolysaccharide (LP...

Dear Editor, We read with great interest the recent article comparing the mechanisms under muscle wasting in quadriceps and diaphragm using an animal model by Mangner et al. While muscle wasting in heart failure (HF) patients is associated with poor exercise capacity and prognosis, current clinical evidences in therapeutic approach have been limited to ones by exercise training. As the author r...

BACKGROUND Progressive loss of skeletal muscle, termed muscle wasting, is a hallmark of cancer cachexia and contributes to weakness, reduced quality of life, as well as poor response to therapy. Previous studies have indicated that systemic host inflammatory response regarding tumor development results in muscle wasting. However, how tumor directly regulates muscle wasting via tumor-derived sec...

Disease control by managers is a crucial response to emerging wildlife epidemics, yet the means of control may be limited by the method of disease transmission. In particular, it is widely held that population reduction, while effective for controlling diseases that are subject to density-dependent (DD) transmission, is ineffective for controlling diseases that are subject to frequency-dependen...

Emerging infectious diseases threaten wildlife populations and human health. Understanding the spatial distributions of these new diseases is important for disease management and policy makers; however, the data are complicated by heterogeneities across host classes, sampling variance, sampling biases, and the space-time epidemic process. Ignoring these issues can lead to false conclusions or o...

The impacts of chronic wasting disease (CWD) on hunters’ behavior and beliefs about acceptable management actions are not clearly understood. This article presents findings from an initial phase of a multi-stage, multi-state effort to address these knowledge gaps. Data were obtained from mail surveys (n = 659) of resident and nonresident deer hunters in eight states and elk hunters in three sta...