A fucoidan discovered in the plant Fucus vesiculosus, which lowered molecular weight of fucoidan, was ideal for its application pharmaceutical and food sectors. The aim to study impact ultrasound process parameters on weight, structure, antioxidant activity fucoidan. For optimization sonochemical such as temperature, sonication time, power (intensity), Box–Behnken design (BBD) through response ...

The bile salt export pump (BSEP, ABCB11) is predominantly responsible for the efflux of bile salts, and disruption of BSEP function is often associated with altered hepatic homeostasis of bile acids and cholestatic liver injury. Accumulating evidence suggests that many drugs can cause cholestasis through interaction with hepatic transporters. To date, a relatively strong association between dru...

Lens epithelial cells differentiate into lens fibers (LFs) in response to a fibroblast growth factor (FGF) gradient. This cell fate decision requires the transcription factor Prox1, which has been hypothesized to promote cell cycle exit in differentiating LF cells. However, we find that conditional deletion of Prox1 from mouse lenses results in a failure in LF differentiation despite maintenanc...

1 Department of Neurology, University Hospital Zurich, 8091 Zurich, Switzerland 2 Division of Neuropsychology, Institute of Psychology, University of Zurich, 8050 Zurich, Switzerland 3 Department of Psychiatry, University Hospital Zurich, 8091 Zurich, Switzerland 4 Institute for Biomedical Engineering, University and ETH Zurich, 8091 Zurich, Switzerland 5 Zurich Centre for Integrative Human Phy...

The potential environmental and human health impacts of artisanal mining of electronic waste through open incineration were investigated. A market-representative set of cellphones was dismantled into four component categories-batteries, circuit boards, plastics and screens. The components were shredded, sieved and incinerated at 743-818 °C. The concentrations of 17 metals were determined using ...

will occur before return to an unparalyzed state following 1 mg/kg intravenous succinylcholine. Anesthesiology 1997; 87: 979–82 7 Gerig H, Schnider T, Heidegger T. Prophylactic percutaneoustranstracheal catheterisation in the management of patients with anticipated difficult airways: a case series. Anaesthesia 2005; 60: 801–5 8 Popat M, Mitchell V, Dravid R, Patel A, Swampilli C, Higgs A. Diffi...

Using a freezing point depression method, requiring volumes of only 200 nanoliters, the osmolalities of 324 tear samples collected at consecutive 10-minute intervals throughout 8.5-hour periods from each of six healthy young adults were measured. The population mean was found to be 318 mOsm/kg, with a population median of 315 mOsm/kg. Individual subject means ranged from 310 to 334 mOsm/kg. Sho...