In the present study, we characterized the antioxidant and hepatoprotective mechanisms underlying of wild grape seed procyanidins (WGP) against oxidative stress damage in ethanol-treated HepG2 cell and Sprague-Dawley (SD)-rat models. In HepG2 cells, WGP not only diminished the ethanol (EtOH, 100 mM)-induced reactive oxygen species (ROS) formation and cytochrome P450 2E1 (CYP2E1) expression, but...

Nanotechnology enables the fabrication of wire-grid polarizers ~WGP! in the visible optical region. At oblique angles of incidence, WGP can be used as polarizing beam splitters ~PBS!. As such, they have the advantages of large numerical aperture and high-extinction ratios in both transmission and reflection. Because of these properties, WGP is being explored as PBS replacement in projectors. In...

Warped Gaussian processes (WGP) [1] model output observations in regression tasks as a parametric nonlinear transformation of a Gaussian process (GP). The use of this nonlinear transformation, which is included as part of the probabilistic model, was shown to enhance performance by providing a better prior model on several data sets. In order to learn its parameters, maximum likelihood was used...

This randomized, placebo-controlled, double-blind study compared the effects of daily supplementation for 4 week with 250 mg Wellmune WGP® β-1,3/1,6-Glucan (WGP) with placebo 250 mg/day (rice flour) on physical and psychological health attributes of self-described "moderate" ragweed allergy sufferers. Study participants (mean age = 36 ± 9 year; range 18-53 year) were recruited before the beginn...

the problem of staff scheduling at a truck hub for loading and stripping of the trucks is an important and difficult problem to optimize the labor efficiency and cost. the trucks enter the hub at different hours a day, in different known time schedules and operating hours. in this paper, we propose a goal programming to maximize the labor efficiency via minimizing the allocation cost. the propo...

This study investigates subcarrier and power allocation schemes in an OFDMA downlink system. To consider client demands, a goal programming approach is proposed. The proposed algorithm minimizes the weighted sum of each client’s dissatisfaction index. Simulations show that the sum of dissatisfaction indices can be reduced significantly. key words: OFMDA, downlink, subcarrier and power allocatio...

this paper will investigate the optimum portfolio for an investor, taking into account 5 criteria. the mean variance model of portfolio optimization that was introduced by markowitz includes two objective functions; these two criteria, risk and return do not encompass all of the information about investment; information like annual dividends, s&p star ranking and return in later years which...

Waste management is the first priority for many countries, so focus of this research on using waste materials in concrete as fillers and substituting ingredients such crumb rubber (CR) fine aggregates. The utilization has gained attention recently, but CR substitution results a reduction mechanical durability properties due to weak bonding lower stiffness CR. To overcome issue, addition strengt...