In wide fan-in dynamic multiplexers, the two phase evaluate-precharge operation leads to high switching activity at the dynamic and the output nodes introducing a significant power penalty. To address this issue, the switching-aware design techniques are being explored but these existing techniques suffer from design inflexibilities. In this paper, we propose a pulse domino switching-aware tech...

The WD-40 repeat protein FAN binds to a distinct domain of the p55 receptor for tumor necrosis factor (TNF) and signals the activation of neutral sphingomyelinase (N-SMase). To analyze the physiological role of FAN in vivo, we generated FAN-deficient mice by targeted gene disruption. Mice lacking a functional FAN protein do not show any overt phenotypic abnormalities; in particular, the archite...

Generation of proapoptotic sphingolipids by neutral sphingomyelinase activation is an early response to hypoxia/reoxygenation (HR) in cardiomyocytes. Factor associated with neutral sphingomyelinase activation (FAN) mediates activation of sphingomyelinase and subsequent apoptosis. However, the participation of FAN in HR-induced cardiomyocyte cell death has not been elucidated. We therefore inves...

The Gröbner fan of an ideal I ⊂ k[x1, . . . , xn], defined by Mora and Robbiano, is a complex of polyhedral cones in Rn. The maximal cones of the fan are in bijection with the distinct monomial initial ideals of I as the term order varies. If I is homogeneous the Gröbner fan is complete and is the normal fan of the state polytope of I. In general the Gröbner fan is not complete and therefore no...

We consider the evolution of black widow pulsars (BWPs). The large majority of these are members of globular clusters. For minimum companion masses < 0.1M ̄, adiabatic evolution and consequent mass loss under gravitational radiation appear to provide a coherent explanation of all observable properties. We suggest that the group of BWPs with minimum companion masses ∼> 0.1M ̄ are systems relaxing ...

Celebrity and fandom have been studied extensively in real life. However, with more and more celebrities using social media, the dynamics of interaction between celebrities and fans has changed. Using data from a set of 57,000 fans for the top followed celebrities on Twitter, we de ne a wide range of features based on their Twitter activity. Using factor analysis we nd the most important factor...

background : the application of ventilation systems in industries and workplaces is with the aim of improving environmental conditions for employees. the lack of appropriate ventilation system components design and control methods result in the production of sound and vibration in most components. the purpose of this study was to determine the role of the pad isolator in controlling vibration a...