Beta-adrenergic agonists induce protein kinase A (PKA) phosphorylation of the cardiac myofilament proteins myosin binding protein C (cMyBP-C) and troponin I (cTnI), resulting in enhanced systolic function, but the relative contributions of cMyBP-C and cTnI to augmented contractility are not known. To investigate possible roles of cMyBP-C in this response, we examined the effects of PKA treatmen...

The current trend in US public housing redevelopment is to replace existing high-rise, high density 'projects' with new lower density, mixed-income communities. The underlying assumption is that mixing together market rate and public housing units will result in social interaction of low-income and middle-income families, which in turn is to provide greater opportunities and reduce social isola...

1474-0346/$ see front matter 2008 Elsevier Ltd. A doi:10.1016/j.aei.2008.07.001 * Corresponding author. Tel.: +886 2 33664313; fax E-mail addresses: [email protected] (C.(S.-C. Kang), [email protected] (S.-H. Hsieh), rex@c This paper presents the experiences of improving an existing surveyor-training tool, called SimuSurvey, using a user-centered approach. As few users were involved during ...