a chronic wound is a wound that does not heal in an orderly set of stages and in a predictable amount of time or wounds that do not heal within three months are often considered chronic. chronic wounds often remain in the inflammatory stage for too long and may never heal or may take years. chronic wound patients often report pain as dominant in their lives. persistent pain is the main problem ...

in the present investigation, methanolic extract of mimusops elengi  leaves were evaluated for wound healing activity. entire wound healing process is complex series of events that begins at the moment of injury and can continue for months to years. methanolic extract of mimusops elengi leaves were examined for wound healing activity in the form of ointment by the excision, the incision and dea...

wounds and wound healing have always been one of the most important subjects that experimental researches were dedicated to. simvastatin has been used for long as a common lipid lowering agent which was reported to have some pleiotropic effects such as antioxidation, anti-inflammation and immunomodulation. in this study we aimed to determine the effect of simvastatin on wound healing process in...

burns are a worldwide problem. the incidence of severe burns has been higher than the combined incidence of tuberculosis and hiv infections. throughout history there have been many different treatments prescribed for burns. the canon is the masterpiece of avicenna’s medical books. the canon includes a description of 785 simple drugs. avicenna believed in burn treatment, which follows two goals....

BACKGROUND Different parts including the latex of Ficus racemosa L. has been used as a medicine for wound healing in the Ayurveda and in the indigenous system of medicine in Sri Lanka. This plant has been evaluated for its wound healing potential using animal models. The aim of this study was to obtain an insight into the wound healing process and identify the potential wound healing active sub...

The application of blood plasma for soft tissue wound healing is receiving much more attention recently. Exosomes are critical paracrine mediators that can be obtained from biological fluids including plasma and be able to induce regenerative effects by transferring bioactive molecules such as microRNAs (miRNAs). This study aimed to investigate the effects of exosomes from human umbilical cord ...

BACKGROUND Drugs of plant origin such as Arnica montana, Calendula officinalis or Hypericum perforatum have been frequently used to promote wound healing. While their effect on wound healing using preparations at pharmacological concentrations was supported by several in vitro and clinical studies, investigations of herbal homeopathic remedies on wound healing process are rare. The objective of...

- healing of surgical wounds and their complications such as infection or scar formation are of major concern in surgery. tissue glues are advanced to reduce these problems. in a prospective study, we have evaluated surgical wound healing in 76 patients whose surgical wounds were repaired by tissue glues (histoacryl). this study was performed in four leaching hospitals (sina, shariaty, shohada,...

Background: Colorectal cancer (CRC) is one of the most common causes of cancer-related death in the world. The expression of N-myc downstream-regulated gene 2 (NDRG2) is down-regulated in CRC. The aim of this study was to investigate the effect of NDRG2 overexpression on cell proliferation and invasive potential of SW48 cells.Methods: SW48 cells were transfected with a plasmid overexpressing ND...