autistic disorders (ads) are neuro-developmental disorders in the category of pervasive developmental disorders chiefly described by three main deficits: 1) deviant communication, 2) impaired reciprocal social interaction, and 3) limited, repetitive and stereotypic patterns of behaviors or interests 1. the world-wide prevalence of ads is estimated to be 62/10,000 1. although various treatment r...

We previously reported a novel rhabdovirus produced from the Spodoptera frugiperda Sf9 cell line, designated as Sf-rhabdovirus X+ since it contained unique accessory gene X. The genome sequence was generated using Sanger sequencing and short-read high-throughput (HTS). In this study, we have used long-read HTS technologies, PacBio’s single-molecule real-time Oxford’s Nanopore RNA direct sequenc...

multiple sclerosis (ms) is an inflammatory demyelinating disease of the central nervous system. it is a clinically heterogeneous disorder especially in terms of disease severity. current investigations suggest that genes and gene-gene interactions not only influence on susceptibility to ms but also affect the disease severity. in this study, we investigated the contribution of the hladrb1*1501 ...

Rett syndrome (RS) is a neurodevelopmental infantile disease characterized by an early normal psychomotor development followed by a regression in the acquisition of normal developmental stages. In the majority of cases, it leads to a sporadic mutation in the MECP2 gene, which is located on the X chromosome. However, this syndrome has also been associated with microdeletions, gene translocations...