BACKGROUND There is an increasing body of published cost-utility analyses of health interventions which we sought to draw together to inform research and policy. METHODS To achieve consistency in costing base and policy context, study scope was limited to Australian-based cost-effectiveness analyses. Through a comprehensive literature review we identified 245 health care interventions that me...

Background: Cardiovascular (CV) diseases remain a leading and costly cause of death globally. Patients with previous CV events are at high risk recurrence. Secondary prevention therapies improve factor control reduce disease costs. Objectives: To assess the cost-effectiveness polypill strategy (CNIC-Polypill) compared loose combination monocomponents to factors in patients coronary heart or str...

Introduction The Spanish Ministry of Health asked us about the efficiency extending current rotavirus vaccination strategy to all newborns. is vaccinate only high-risk newborns (premature and those qualified as by a pediatrician). objective this research was compare three strategies: no-vaccination, universal vaccination, considering two vaccines available in Spain: RotaTeq® Rotarix®. Methods A...

Abstract Background The payment card (PC) format and the open-ended (OE) are common methods in eliciting willingness-to-pay (WTP) of one additional quality-adjusted life year (QALY). aim this research is to compare these two formats monetary value a QALY. Methods A contingent valuation survey was carried out using pre-designed questionnaire with various hypothetical scenarios. difference betwee...

BACKGROUND Health-state preferences can be combined with willingness-to-pay (WTP) data to calculate WTP per quality-adjusted life year (QALY). The WTP/QALY ratios provide insight into societal valuations of expenditures for medical interventions. METHODS The authors measured preferences for current health in 3 patient populations (N = 391) using standard gamble, time trade-off, visual analog ...

BACKGROUND The choice between sleeve lobectomy and pneumonectomy is controversial for patients with early-stage lung cancer and who have acceptable lung function. METHODS We performed a meta-analysis of results of sleeve lobectomy and pneumonectomy published in English from 1990 to 2003. A decision model was developed with 5-year survival, quality-adjusted life years (QALY), and cost effectiv...

BACKGROUND National guidance on preventing type 2 diabetes mellitus (T2DM) in the UK recommends low-intensity lifestyle interventions for individuals with intermediate categories of hyperglycaemia defined in terms of impaired fasting glucose (IFG) or 'at-risk' levels of HbA1c. In a recent systematic review of economic evaluations of such interventions, most studies had evaluated intensive trial...

BACKGROUND To evaluate the cost-effectiveness of growth hormone (GH) treatment (Genotropin®) compared with no GH treatment in adults with GH deficiency in a Swedish societal setting. METHODS A Markov-type cost-utility simulation model was constructed and used to simulate, for men and women, morbidity and mortality for GH-treated and -untreated individuals over a 20-year period. The calculatio...

OBJECTIVE The purpose of this study was to determine the cost-utility of treating anemic dialysis patients with continuous erythropoietin receptor activator (CERA) once monthly or Epoetin Beta (EpoB) thrice weekly compared with a reference strategy of managing anemia with red blood cell transfusion (RBCT). METHODS Cost-utility analysis study design. Decision analysis model, National health ca...

STUDY DESIGN Cost-effectiveness analysis. OBJECTIVE To examine the cost-effectiveness of operative versus non-operative treatment of type-II odontoid fractures in patients older than 64 years old. SUMMARY OF BACKGROUND DATA Significant controversy exists regarding the optimum treatment of geriatric patients with type-II odontoid fractures. Operative treatment leads to lower rates of non-uni...