in this study fungi isolated from the effluent of ethanol factories were identified. optimal conditions for single cell protein (scp) production and cod reduction of sugar beet stillage are specified for a species of hansenula in a continuous culture. under these conditions 5.7 g dm-3 biomass was produced and 31% of cod was reduced without addition of further nutrients to the beet molasses stil...

Numerous bacterial pathogens manipulate host cell processes to promote infection and ultimately cause disease through the action of proteins that they directly inject into host cells. Identification of the targets and molecular mechanisms of action used by these bacterial effector proteins is critical to understanding pathogenesis. We have developed a systems biological approach using the yeast...

Candida species represent a major fungal threat for human health. Within the genus, yeast albicans is most frequently incriminated during episodes of candidiasis or candidemia. Biofilm formation used by C. to produce microbial community that important in an infectious context. The cell wall, superficial cellular compartment, paramount importance regarding establishment biofilms. wall contains p...

The yeast cell wall plays an important role in maintaining cell morphology, cell integrity and response to environmental stresses. Here, we report that salt stress causes cell wall damage in yeast cells lacking mitochondrial DNA (ρ0). Upon salt treatment, the cell wall is thickened, broken and becomes more sensitive to the cell wall-perturbing agent sodium dodecyl sulfate (SDS). Also, SCW11 mRN...

Molecular chaperones, such as Hsp40, regulate cellular processes by aiding in the folding, localization, and activation of multi-protein machines. To identify new targets of chaperone action, we performed a multi-copy suppressor screen for genes that improved the slow-growth defect of yeast lacking the YDJ1 chromosomal locus and expressing a defective Hsp40 chimera. Among the genes identified w...