Sleep is essential for physical and niental health. In the last 15 years there has grown up the concept of the brain stem reticular activating system. Electroencephalographic studies have shown two qualitatively different and alternat ing kinds of sleep, the orthodox (“slowwave―, or “¿ fore-brain―) and the paradoxical (“hind brain―, “¿ rapid eye movement―, “¿ activated―, or ...

 The research on social networks and collaborative strategies has highlighted from the mid of 1980 which has contributed to the success and development of firms. The relationship and communication with trade partners in overseas help success of firms in entering to foreign markets and improve new partners and new markets abroad. Doing firm internationalization in foreign countries faces some ba...

C —¿ > T transitions at CpG sites are the most prevalent mutations found in the p53 tumor suppressor gene in human colon tumors and in the germline (Li-Fraumeni syndrome). All of the mutational hot spots are methylated to 5-methylcytosine, and it has been hypothesized that the majority of these mutations are caused by spontaneous hydrolytic deamination of this base to thymine. We have previou...

o-2-Macroglobulin («2M)was demonstrated in normal and mildly dysplastic cervical epithelium using immunohistochemical methods. In contrast, staining for «2Mdiminished gradually with advancing epithelial dysplasia and was totally negative in truly neoplastic lesions. No in vitro synthesis could be detected in cultured ectocervical cells or in a corresponding malignant cell line (HeLa). However...

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C —¿ > T transitions at CpG sites are the most prevalent mutations found in the p53 tumor suppressor gene in human colon tumors and in the germline (Li-Fraumeni syndrome). All of the mutational hot spots are methylated to 5-methylcytosine, and it has been hypothesized that the majority of these mutations are caused by spontaneous hydrolytic deamination of this base to thymine. We have previou...

The asymmetric nature of the boson ‘destruction’ operator â and its ‘creation’ partner ↠is made apparent by applying them to a quantum state |ψ〉 different from the Fock state |n〉. We show that it is possible to increase (by many times or by any quantity) the mean number of quanta in the new ‘photonsubtracted’ state â|ψ〉. Moreover, for certain ‘hyper-Poissonian’ states |ψ〉 the mean number of q...

Highly DNA-reactive <*,/3-unsaturated aldehydes such as acrolein and crotonaldehyde are common environmental pollutants present in cigarette smoke and automobile exhaust and are also released endogenously by lipid peroxidation. Acroleinand crotonaldehyde-derived l,.V--prop;modeoxyguanosine (AdG and CdG, respectively) have been detected in the tissues of carcinogen-treated rodents and as backgro...