OBJECTIVE The combination of mifepristone and misoprostol is an established method for induction of early first trimester abortion, but there is no consensus about the best evaluation of treatment outcome. We evaluate serum Angiopoietin-2 (Ang-2) and β human chorionic gonadotropin (β-hCG) in women who had undergone a medical abortion as markers of prolonged uterine bleeding (PUB). METHODS Pro...

OBJECTIVE To investigate the slope of linear regression of postevacuation serum hCG as an independent risk factor for postmolar gestational trophoblastic neoplasia (GTN). DESIGN Multicenter retrospective cohort study. SETTING Academic referral health care centers. PATIENT(S) All subjects with confirmed hydatidiform mole and at least four measurements of β-hCG titer. INTERVENTION(S) None...

Amaç: Gebeliği doğrulama ve sonucunu daha erken aşamada tahmin edebilmeye yönelik maternal serum belirteçleri arasında β-human koryonik gonadotropin (β-hCG) yüksek duyarlılık güvenirlilik sağlayan bir biyobelirteçtir. Yapılan çalışmalar, tek gündeki β-hCG ölçümüne ek olarak değerinin artma seyrinin de gebelik öngörmede yararlı olduğunu bildirmiştir. Çalışmamızda ICSI işlemlerini takiben dönem a...

Women with ectopic pregnancies tend to have lower β-human chorionic gonadotropin (β-hCG) levels than women with intrauterine pregnancies (IUP) [1]. Transvaginal ultrasound (TVUS) is capable of detecting IUPs when β-hCG levels are greater than 1500 mIU/mL, the so-called discriminatory zone [2–4]. When serum β-hCG levels are less than 1500 mIU/mL and no IUP is detected, possibility of ectopic pre...

BACKGROUND AND AIM Preeclampsia remains a major problem of modern obstetrics with insufficiently elucidated etiology; early detection would diminish maternal and fetal mortality and morbidity. The aim of this study was to determine the serum values of β-hCG in the first and second trimesters of pregnancy and PAPP-A values in the first trimester of pregnancy in pregnant women with risk factors f...

OBJECTIVE To investigate the potential value of maternal serum concentrations of free β-human chorionic gonadotrophin (β-hCG), pregnancy-associated plasma protein-A (PAPP-A) and placental growth factor (PlGF) at 30-33 weeks of gestation in the prediction of pre-eclampsia (PE) developing at or after 34 weeks. METHODS Serum free β-hCG, PAPP-A and PlGF were measured at 11-13 and at 30-33 weeks o...

STUDY OBJECTIVE We seek to assess the performance of the β human chorionic gonadotropin (β-hCG) "discriminatory zone" when using bedside pelvic ultrasonography in the evaluation of symptomatic pregnant emergency department (ED) patients. METHODS This was a cross-sectional study of bedside pelvic ultrasonography performed on consecutive pregnant patients in the first trimester who presented to...

BACKGROUND A subset of women with a tubal ectopic pregnancy can be safely managed expectantly. Expectant management involves a degree of disruption with hospital visits to determine serum β-hCG (β-human chorionic gonadotrophin) concentration until the pregnancy test becomes negative and expectant management is considered complete. The length of time required for the pregnancy test to become neg...

OBJECTIVE To examine the association between maternal serum levels of thyroid stimulating hormone (TSH) and free β-human chorionic gonadotrophin (free β-hCG) in trisomy 21, trisomy 18 and euploid pregnancies at 11-13 weeks and investigate the potential value of TSH in first-trimester screening for aneuploidies. METHODS Maternal serum TSH and free β-hCG levels at 11-13 weeks in 25 trisomy 21 a...