Iran is the main producer of Saffron in the world and a great number of Khorasan (the largest province of Iran) are involved in growing this plant. Recently, saffron pollen has found great importance due to inducing allergic reactions. In this study, the prevalence and clinical symptoms of saffron pollen allergy and specific IgE level in saffron workers have been studied. For this purpose, 167 ...

Mol. Nutr. Food Res. 2021, 65, 202100536 DOI: 10.1002/mnfr.202100536 IgE-mediated food allergies (IgE-FA) are considered a growing epidemic. Its pathogenic mechanisms remain however largely unknown. The authors performed literature search followed by in-depth pathway mapping of IgE-FA in children, and revealed shift energy metabolism, next to aberrant metabolization bile acids, lipids, nucleoti...

Background and Purpose: Aspergillus fumigatus as a ubiquitous fungus can be found in the respiratory tract of the asthmatic and healthy people. The inhalation of Aspergillus spores leads to an immune response in individuals with asthma and results in the aggravation of the clinical symptoms. The present study aimed to investigate the prevalence of specific immunoglobulin E and G (IgE and IgG) a...

asthma is a complex and multifactorial disorder. several studies have reported association between different hla- dqb1 and hla- drb1 alleles and allergic asthma. the aim of the present study was to investigate the association of hla-class ii alleles and haplotypes, with total serum ige and the results of the skin prick test in iranian children with allergic asthma. a total of 112 patients with ...