Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of three malignancies associated with AIDS and immunosuppression. Tumor cells harbor latent virus and express kaposin (open reading frame [ORF] K12), v-FLIP (ORF 71), v-Cyclin (ORF 72), and latency-associated nuclear antigen (LANA; ORF 73). ORFs 71 to 73 are transcribed as multicistronic RNAs initiating from adjacent constitu...

cin B2) and S'^-dideoxyneamine^ have confirmed that removal of the hydroxyl group which is phosphorylated by drug-resistant bacteria from kanamycins gives compounds active against the resistant organisms. As an extension of this work, we describe in this paper the syntheses of two deoxy-derivatives of ribostamycin4). If inactivation of ribostamycin by Escherichia coli K12-ML 1629 and K12-ML 163...

The repeat unit of the K12 capsular polysaccharide isolated from the Acinetobacter baumannii global clone 1 clinical isolate, D36, was elucidated by means of chemical and spectroscopical methods. The structure was shown to contain N-acetyl-D-galactosamine (D-GalpNAc), N-acetyl-D-fucosamine and N-acetyl-L-fucosamine linked together in the main chain, with the novel sugar, 5,7-diacetamido-3,5,7,9...

Let Kq(n,R) denote the minimal cardinality of a q-ary code of length n and covering radius R. Recently the authors gave a new proof of a classical lower bound of Rodemich on Kq(n, n−2) by the use of partition matrices and their transversals. In this paper we show that, in contrast to Rodemich’s original proof, the method generalizes to lower-bound Kq(n, n − k) for any k > 2. The approach is bes...

In this paper we describe the generation of all nonorientable triangular embeddings of the complete graphs K12 and K13. (The 59 nonisomorphic orientable triangular embeddings of K12 were found in 1996 by Altshuler, Bokowski and Schuchert, and K13 has no orientable triangular embeddings.) There are 182, 200 nonisomorphic nonorientable triangular embeddings for K12, and 243, 088, 286 for K13. Tri...

The major outer membrane protein patterns of 45 Escherichia coli strains of human origin were compared with that of E. coli K12 by sodium dodecyl sulphate-polyacrylamide gel electrophoresis. Preparations of the former strains contained between two and five major bands in the molecular weight range between 30 000 and 42 000. The patterns were very heterogeneous with respect to the numbers and el...

PURPOSE To detect and isolate cells with stem cell (SC) characteristics in the limbus of the mouse. METHODS Limbal tissues from BALB/c mice were trypsin-dissociated and separated on the gradient Percoll (Fluka, Buchs, Switzerland). Several fractions were isolated and characterized by real-time PCR for the presence of limbal SC markers and differentiation markers of corneal epithelial cells by...

Quantifying the effect that nanofiber mat chemistry and hydrophilicity have on microorganism collection and inactivation is critical in biomedical applications. In this study, the collection and inactivation of Escherichia coli K12 was examined using cellulose nanofiber mats that were surface-functionalized using three polyelectrolytes: poly (acrylic acid) (PAA), chitosan (CS), and polydiallyld...

We explore whether early childhood human-capital investments are complementary to those made later in life. Using the Panel Study of Income Dynamics, we compare the adult outcomes of cohorts who were differentially exposed to policy-induced changes in pre-school (Head Start) spending and school-finance-reform-induced changes in public K12 school spending during childhood, depending on place and...