the previous large retrospective studies demonstrated that treatment with statins reduces both the incidence of prostate cancer by 50% and serum prostate specific antigen (psa) level up to 40%. however the main problem in those studies was the absence of control groups of men with hypercholesterolemia without statin treatment. we performed a small prospective controlled clinical trial to assess...

Background: Prostate specific antigen (PSA) is an important biomarker to monitor patients after treated with radiation therapy (RT). The aim of this study is to evaluate the relationship between the PSA data and prostate cancer recurrence using the joint modeling. Methods: This historical cohort study was performed on 422 prostate cancer patients. Inclusion criteria included: patients with loc...

background: the serum prostate specific antigen (psa) levels are used for prostate cancer screening. some conditions such as prostatitis, manipulation, and prostate cancer could influence on serum psa. the impact of ejaculation on serum psa is controversial. the aim of our study was to evaluate the relation of ejaculation and the levels of serum psa. materials and methods: in this cross-section...

conclusions psa, psa density, and gleason score should be considered together in order to more accurately predict the adverse pathologic features of prostate cancer. methods we conducted a cross-sectional study of 105 patients with localized prostate cancer who underwent radical prostatectomy between 2006 and 2013. we recorded gleason scores and psa levels, in addition to the results of patholo...

background: prostate specific antigen (psa) is an important laboratory marker for diagnosis of prostatic cancer. thus, development of diagnostic tools specific for psa plays an important role in screening, monitoring and early diagnosis of prostate cancer. in this paper, the production and characterization of a panel of murine monoclonal antibodies (mabs) against psa have been presented.  metho...