BACKGROUND/AIMS Preeclampsia (PE) is a systemic inflammatory response syndrome involving varieties of cytokines, and previous studies have shown that IL-33 and its receptor IL-1RL1 play pivotal roles in the development of it. As a polygenetic hereditary disease, it is necessary to study the gene analysis for PE. Therefore, the present study was to determine whether IL-33 rs3939286 and IL-1RL1 r...

Physiological processes such as ovarian follicle atresia generate large amounts of unnecessary cells or tissue detritus, which needs to be disposed of rapidly. IL-33 is a member of the IL-1 cytokine gene family. Constitutive expression of IL-33 in a wide range of tissues has hinted at its role beyond immune defense. We have previously reported a close correlation between IL-33 expression patter...

This case report presents the performance of an athlete who completed for the first time in history the total distance of 33 Ironman triathlons within 33 consecutive days. The athlete finished the total distance of 7,458 km (i.e. 125 km swimming, 5,940 km cycling and 1,393 km running) within a total time of 410 h and a mean time of 12 h 27 min per Ironman distance. During the 33 days, the athle...

The cytokine network controlling basophils has been extended to interleukin-33. This commentary provides an update and summary on this emerging concept.