Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric that has significant effect on the quality of life. The most effective treatment for OCD combination selective serotonin reuptake inhibitors (SSRI) with cognitive behavior therapy (CBT). However, several adverse effects have been linked this usual pharmacotherapy, and it unsuccessful in many patients. exact pathophysiology not co...

Individuals with obsessive-compulsive disorder (OCD) commonly experience comorbid mood disturbances such as major depressive disorder (MDD). Previous studies that have compared OCD patients with and without MDD have revealed differences in demographic characteristics, clinical severity, and symptom presentation between these two patient groups. Previous studies have not, however, examined wheth...

BACKGROUND Obsessive-compulsive disorder (OCD) has been associated with impairments in stop-signal inhibition, a measure of motor response suppression. The study used a novel paradigm to examine both thought suppression and response inhibition in OCD, where the modulatory effects of stimuli relevant to OCD could also be assessed. Additionally, the study compared inhibitory impairments in OCD pa...

Body dysmorphic disorder (BDD) and eating disorders are body image disorders that have long been hypothesized to be related to obsessive-compulsive disorder (OCD). Available data suggest that BDD and eating disorders are often comorbid with OCD. Data from a variety of domains suggest that both BDD and eating disorders have many similarities with OCD and seem related to OCD. However, these disor...

Background: Occupational contact dermatitis (OCD) is an inflammatory response caused by with allergens or irritants in the work environment, and this disease most often found as occupational disease. Personal protective equipment (PPE) a safety tool that must be used workers to protect body from possible potential hazards workplace. Construction workers, woodworkers, batik farmers can take prev...

Gilles de la Tourette Syndrome (GTS) and obsessive-compulsive disorder (OCD) share obsessive-compulsive phenomena. The aims of this study were to compare the OC symptom distribution between GTS and OCD and to investigate whether a subdivision of these phenomena into obsessions, compulsions and 'impulsions' is useful in distinguishing GTS and OCD patients. Thirty-two GTS, 31 OCD (10 with tics, 2...

BACKGROUND Recent data from neuroimaging, genetic and clinical trials and animal models suggest a role for altered glutamatergic neuro transmission in the pathogenesis of obsessive-compulsive disorder (OCD). The aim of this study was to investigate whether variants in the GRIN2B gene, the gene encoding the NR2 subunit of the N-methyl-D-aspartate (NMDA) glutamate receptor, may contribute to gene...

OBJECTIVE Repeated experience with stimuli often primes faster, more efficient neuronal and behavioural responses. Exaggerated repetition priming effects have previously been reported in obsessive-compulsive disorder (OCD), however little is known of their underlying neurobiology or disorder-specificity, hence we investigated these factors. METHODS We examined event-related potentials (ERPs) ...

Traditionally, osteochondritis dissecans (OCD) has been thought of as a rare disorder occurring in approximately 15 to 21 per 100,000 knees.1 However, OCD is becoming increasingly more common as a cause of knee pain in teenagers and young adults. This may be due to earlier and increasingly competitive athletic endeavors.2 In addition, the widespread use of magnetic resonance imaging (MRI) as a ...

Clinical and neurobiological evidence suggests that concurrent presentation of schizophrenia and obsessive-compulsive (schizo-OCD) symptoms represents a distinct clinical entity. Given that obsessive-compulsive disorder (OCD) and schizophrenia have been modeled as having different neurofunctional profiles, the overlap between them represents a heuristic challenge for cognitive and endophenotype...