We have identified and characterized a secreted protein, designated Pic, which is encoded on the chromosomes of enteroaggregative Escherichia coli (EAEC) 042 and Shigella flexneri 2457T. The product of the pic gene is synthesized as a 146.5-kDa precursor molecule which is processed at the N and C termini during secretion, allowing the release of a mature protein (109.8 kDa) into the culture sup...

In this letter, adaptive multi-stage parallel interference cancellation (PIC) receiver is considered for multi-rate DS-CDMA system. In each stage of the adaptive multi-stage PIC receiver, multiple access interference (MAI) estimates are obtained by the sub-bit estimates from the previous stage and the adaptive weights for the sub-bit estimates. The adaptive weights are obtained by minimizing th...

Persistent inward current (PIC) plays an important role in setting the input-output gain of motoneurons. In humans, these currents are estimated by calculating the difference between synaptic input at motor unit recruitment and derecruitment (ΔF) derived from paired motor unit recordings. The primary objective of this study was to use the relationship between reciprocal inhibition (RI) and PIC ...

Previous studies in our laboratory have demonstrated that focal injections of picolinic acid (PIC) protect the cholinergic neurons of the nucleus basalis magnocellularis (nbm) against quinolinic acid (QUIN)-induced neurotoxicity. The present study was designed to examine the effects of chronic infusions of QUIN and PIC on nicotinamide adenine dinucleotide (NADPH) diaphorase containing neurons o...

In the months after spinal cord injury, motoneurons develop large voltage-dependent persistent inward currents (PICs) that cause sustained reflexes and associated muscle spasms. These muscle spasms are triggered by any excitatory postsynaptic potential (EPSP) that is long enough to activate the PICs, which take > 100 ms to activate. The PICs are composed of a persistent sodium current (Na PIC) ...

We have reanalyzed data for the proposed moving group associated with β Pictoris in order to determine if the group (or part of it) is real, and, if so, to derive an improved age estimate for β Pic. By using new, more accurate proper motions from PPM and Hipparcos and a few new radial velocities, we conclude that on kinematic grounds most of the proposed members of the moving group are not, in ...

This paper investigates the scope of usage of fuzzy logic to beat the effect of multiple access interference (MAI) through block parallel interference cancellation (BPIC) in a synchronous Carrier Interferometry/MC-CDMA uplink system. The users are classified in different blocks like very strong, strong, weak and very weak based on fuzzy membership function derived from the magnitude of the rece...

36 The central hub of the cortical vestibular network in humans is likely localized in the region 37 of posterior lateral sulcus. An area characterized by responsiveness to visual motion has 38 previously been described at a similar location and named posterior insular cortex (PIC). 39 Currently it is not known whether PIC processes vestibular information as well. We localized 40 PIC using visu...

Polyriboinosinic-polyribocytoidylic acid (pIC), a synthetic dsRNA, acts as an adjuvant that boosts immune responses and protection. Intranasal (IN) administration of pIC has recently been used to adjuvant influenza virus vaccines; however, the effects of IN pIC administration on pulmonary T cell responses remain unclear. Here we show that a single IN administered dose of dsRNA into mice induced...

Building on prior research (Meyer, Foster, & Anderson, 2006), the present study examined the utility of three approaches to validate the Performance Improvement Characteristics (PIC; Hogan & Rybicki, 1998). The PIC is a job analysis instrument used to assess personal characteristics important to successful job performance. Hogan Personality Inventory (HPI; Hogan & Hogan, 1995) data in seven arc...