Measurement of a High-Temporal Resolution Arterial Input Function from MR Projections: Extension to Radial Acquisition to Compensate for Local Tissue Enhancement Jen Moroz, Stefan A Reinsberg, and Piotr Kozlowski Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, Radiology, UBC, University of British Columbia, BC, Canada, UBC MRI Research Centre, University of British...

In general, the ultimate bearing capacity (UBC) of shallow foundations on unsaturated soils is characterized by conventional shear strength (SS) parameters in which saturated theories are applied. However, this case, it clear that designed using obtained values from cases not be economical. recent years, procedures have been developed to estimate UBC soils, take into account drained and undrain...

Ubiquitin fusion degradation (UFD) substrates are delivered at the proteasome by a handover mechanism involving the ubiquitin-selective chaperone Cdc48 and the ubiquitin shuttle factor Rad23. Here, we show that introduction of a 20 amino acid peptide extension not only rendered degradation independent of Cdc48, in line with the model that this chaperone is involved in early unfolding events of ...

BACKGROUND Unicameral (or simple) bone cysts (UBC) are benign tumours most often located in long bones of children and adolescents. Pathological fractures are common, and due to high recurrence rates, these lesions remain a challenge to treat. Numerous surgical procedures have been proposed, but there is no general consensus of the ideal treatment. The aim of this investigation therefore was to...

In a yeast two-hybrid screen, RING finger protein 1 (RFP-1) and UBR1 were identified as potential binding partners of C. elegans UBC-1, a ubiquitin-conjugating enzyme with a high degree of identity to S. cerevisiae UBC2/RAD6. The interaction of RFP-1 and UBC-1 was confirmed by co-immunoprecipitation experiments. Yeast interaction trap experiments mapped the region of interaction to the basic N-...

Intravesical adjuvant chemotherapy and neoadjuvant chemotherapy has been respectively administered for superficial transitional cell carcinoma (TCC) of urinary bladder and advanced TCC for years. However, the therapeutic efficacy is limited. Recently, overexpression of aldo-keto reductase (AKR) in lung, esophageal, uterine cervical and ovarian cancers was shown to be closely associated with dis...

Background Urologists are frequently confronted with questions of urinary bladder cancer (UBC) patients about what they can do to improve their prognosis. Unfortunately, it is largely unknown which lifestyle factors can influence prognosis. Objective To systematically review the available evidence on the association between body mass index (BMI), diet, dietary supplements, and physical activi...

Any group that creates challenging goals also requires a strategy to achieve them and process review improve this over time. The University of British Columbia (UBC) set ambitious campus sustainability goals, including reduction in its greenhouse gas emissions 33% below the 2007 level by 2015, 100% 2050 (UBC, 2006). pursued these through number specific projects (such as major district energy u...