Introduction. Currently, there is no unified treatment algorithm of cardiac autonomic neuropathy (CAN) in patients with type 2 diabetes mellitus (T2DM). The aim the study was to investigate effects simvastatin (SIM) and -3 polyunsaturated fatty acids (-3 PUFAs) on blood lipid profile insulin resistance (IR) definite neuropathy. Materials methods. involved 72 T2DM CAN. Patients were divided in...

Particle size of low density (LDL) and high density (HDL) lipoproteins and cholesterol esterification rate in HDL plasma (FER(HDL)) are important independent predictors of coronary artery diseases (CAD). In this study we assessed the interrelations between these indicators and routinely examined plasma lipid parameters and plasma glucose concentrations. In 141 men, healthy volunteers, we examin...

RELATIONSHIP BETWEEN HDL-C AND CARDIOVASCULAR DISEASES: Beyond the role of low-density lipoprotein cholesterol (LDL-c) in the development of atherosclerosis, growing evidence suggest that high-density lipoprotein cholesterol (HDL-c) is a powerful predictor of cardiovascular disease. Indeed, epidemiological, mechanistic and intervention studies suggest that low HDL-c is a major cardiovascular ri...

OBJECTIVES To examine the association between the fractional esterification rate of cholesterol (C) in low density lipoprotein- and very low density lipoprotein-depleted plasma (FER(HDL)) and coronary artery disease (CAD) and the influence of serum HDL-C levels. BACKGROUND The function of HDL in reverse cholesterol transport is involved in the antiatherogenic action of HDL, and FER(HDL) is a ...

Aim: The aim of this study is to understand the pattern dyslipidemia, lipid radicals and antioxidant activities in women with polycystic ovarian syndrome reproductive-aged Nigerian women. Methodology: Original randomized case-control studies assessing comparative patterns panels PCOS Nigeria published between 1st January 2019 31st December 2020 were identified by searching online databases, inc...

Abstract Background Carotid intima-media thickness (cIMT) progression was recently established as a predictor of cardiovascular events among adults. To date, single cIMT measure has largely been used marker preclinical atherosclerotic changes in the young population and dyslipidaemia associated with measured cIMT. The longitudinal relationship between repeated large apparently healthy remains u...

High-density lipoprotein-cholesterol (HDL-C) is one of the most commonly measured biomarkers integrated into public health prevention guidelines. Major epidemiological studies have demonstrated strong, inverse, and independent relationships between HDL-C and cardiovascular disease (CVD) and stroke. However, several recent clinical trials have challenged the value of raising HDL-C pharmacologica...

CONTEXT Cardiovascular disease (CVD) is the largest cause of mortality in Indians. Insulin resistance and related dyslipidemia of increased triglyceride (TG), small dense low-density lipoprotein (sd-LDL) particles, and decreased high-density lipoprotein-cholesterol (HDL-C) are associated with increased risk of CVD. TG/HDL-C ratio could be a potential surrogate marker for this South Asian phenot...