In order to conduct faithful simulations of ocean circulation one needs considerable computational power and storage capabilities. We study the parallelization of a three-dimensional ocean circulation model (OCM) and provide summary results from recent experiments on the Cedar hierarchical architecture. A major goal of our effort is to obtain guidelines for the proper design of OCM codes for pa...

PURPOSE Studies comparing radical prostatectomy (RP) outcomes with those of radiotherapy with or without androgen deprivation therapy (RT±ADT) for prostate cancer (PCa) have yielded conflicting results. Therefore, we used propensity score-matched analysis and competing risk regression analysis to compare cancer-specific mortality (CSM) and other-cause mortality (OCM) between these two treatment...

BACKGROUND Alterations in one-carbon metabolism (OCM) have been observed in patients with schizophrenia (SZ), but a comprehensive study of OCM has not yet been conducted. A carbon atom is transferred from l-serine to methionine during OCM, but the relationship between l-serine and methionine in SZ is not yet known. We investigated the relationship between l-serine and methionine to obtain a com...

This paper presents main ideas and design details of a performance analysis tool – G-PM and a grid application monitoring system – OCM-G for applications running on the Grid which are under development within the EU CrossGrid project. Besides of the operation of G-PM’s components, we overview its internal interfaces. G-PM enables not only standard measurements, but also comprises application-sp...

A central goal of neuroscience is to understand how groups of neurons interact to give rise to the myriad functions of the nervous system. This task is extremely difficult in part because of the technical challenge of recording the electrical activity of many neurons simultaneously without disturbing their environment. Although several methods exist, new techniques are in strong demand. One pro...

We demonstrate how optical coherence imaging techniques can detect intrinsic scattering changes that occur during action potentials in single neurons. Using optical coherence tomography (OCT), an increase in scattering intensity from neurons in the abdominal ganglion of Aplysia californica is observed following electrical stimulation of the connective nerve. In addition, optical coherence micro...

In this contribution the solution of Fractional Optimal Control Problems (FOCP) by using Orthogonal Collocation Method (OCM) and Multi-objective Optimization Stochastic Fractal Search (MOSFS) algorithm is investigated. For purpose, three classical case studies on engineering are considered. Initially, concentration profiles laccase enzyme production process analyzed to evaluate influence fracti...

Understanding the mechanism of angiogenesis could help to decipher wound healing and embryonic development and to develop better treatment for diseases such as cancer. Microengineered devices were developed to reveal the mechanisms of angiogenesis, but monitoring the angiogenic process nondestructively in these devices is a challenge. In this study, we utilized a label-free imaging technique, u...

In this paper, we propose a robust disease detection method, called adaptive orientation code matching (Adaptive OCM), which is developed from a robust image registration algorithm: orientation code matching (OCM), to achieve continuous and site-specific detection of changes in plant disease. We use two-stage framework for realizing our research purpose; in the first stage, adaptive OCM was emp...

We describe the development and utilization of a new imaging technology for plant biology, optical coherence microscopy (OCM), which allows true in vivo visualization of plants and plant cells. This novel technology allows the direct, in situ (e.g. plants in soil), three-dimensional visualization of cells and events in shoot tissues without causing damage. With OCM we can image cells or groups ...