Methylenetetrahydrofolate reductase (MTHFR) is a critical folate-metabolising enzyme which requires riboflavin as its co-factor. A common polymorphism (677C T) in the MTHFR gene results in reduced MTHFR activity in vivo which in turn leads to impaired folate metabolism and elevated homocysteine concentrations. Homozygosity for this polymorphism (TT genotype) is associated with an increased risk...

In early 2003 our team announced the discovery of the second extrasolar transiting planet, around the faint star OGLE-TR-56 (V = 16.6), based on the detection of small changes in the radial velocity of the primary. The star was originally identified as a candidate by the OGLE team from the shallow and periodic dips in its brightness. We present here new precise radial velocity measurements that...

PHILOSOPHY VII 1999 1. Opening WHAT IS THE EPISTEMOLOGICAL STATUS OF OUR KNOWledge of the truths of arithmetic? Are they analytic, the products of pure reason, as Leibniz held? Or are they high-level empirical truths that we know only a posteriori, as some empiricists, particularly Mill, have held? Or was Kant right to say that, although our knowledge that ‘5+7=12’ depends essentially upon intu...

Melanocytic skin tumors are caused by nevus cells, epidermal melanocytes and dermal melanocytes. The aim of the study was to detect the positivity of Demodex spp. in biopsy specimens of skin diagnosed as nevus. In this retrospective study, the specimens obtained from 110 patients diagnosed with nevus and stained by hematoxylin & eosin (H&E) method were assessed for Demodex. Statistical analysis...

49 he liberalization of the world’s energy markets is forcing the electric supply industry to reorganize itself from the ground up. On the one hand, it is expanding to include energy services, power marketing and information technology based services; and on the other, it is increasing asset utilization, reducing maintenance costs, and saving on investments by optimizing operation of the existi...