The metabolism of the suspected carcinogen acrylonitrile was studied using subcellular fractions isolated from rats and humans. Irreversible binding of radioactive label from [1-14C]or [2,3-14C]acrylonitrile to protein and DNA was enhanced by reduced nicotinamide adenine dinucleotide phosphate in the presence of rat liver microsomes or a reconstituted cytochrome P-450 system. During the reduced...

OBJECTIVE Hepatitis B vaccine is recommended for all infants, and the series may be started during the delivery admission. For infants who are born either to women who are positive for hepatitis B surface antigen (HBsAg) or to women whose HBsAg status is unknown, vaccination should be started within 12 hours of birth to prevent perinatal and early childhood hepatitis B virus infection. Because ...

Esse trabalho teve o objetivo de avaliar desempenho clínico das restaurações em resina composta realizadas por acadêmicos com base nos critérios adaptação marginal, textura superficial, reincidência cárie, retenção e cor. A pesquisa ocorreu duas etapas. primeira foi pelo levantamento dados prontuários dos pacientes da Clínica-Escola Odontologia Universidade Regional Integrada do Alto Uruguai Mi...

A draft treaty under consideration by the United Nations Environmental Program has been prepared to greatly reduce global health hazards from environmental mercury. In response to the draft treaty, the World Health Organization urges removal of a provision in the treaty that calls for a ban on thimerosal (which contains ethyl mercury) in vaccines, a position recently endorsed by the American Ac...

Antonia Novello, the Surgeon General o f the United States, w ill address the 1993 graduat­ ing class of Saint Mary's at the College’s 146th annua l com ­ mencement on May 15. More than 400 seniors w ill be aw arded degrees d u rin g the ceremony, which begins at noon in the Le Mans Hall courtyard. Novello, who w ill receive an honorary doctor o f science de­ gree, was sworn in as surgeon g e n...

OHSU Vaccine and Gene Therapy Institute and the Division of Pathobiology, Oregon National Primate Research Center, Beaverton, OR 97006 and the Department of Molecular Microbiology and Immunology of the Oregon Health & Science University, Portland, OR 97201 Note: Supported by the USPHS awards NIA AG 21384 (J. N-Z.) and NCRR P51 RR 00163 (Core National Primate Center Support Grant) from the Natio...

From the Departments of Neurology and Pathology, Cornell University Medical College, New York, N. 1. Supported in part by Research Grants HE-04872 and NB-03346, NB-04161 from USPHS and from the Winthrop Laboratories. Dr. Kutt is a recipient of a Research Career Development Award JKO 3 NB 35003, NINDB, USPH. First submitted October 2, 1968; accepted for publication December 13, 1968. KARL VEREBE...

This in vivo study evaluated the clinical performance and appearance of a flowable resin composite and a hybrid resin composite over two years. Twenty-eight (28) pairs of restorations of a flowable resin composite and a conventional hybrid resin composite were placed in non-carious, asymptomatic facial Class V lesions. The restorations were evaluated at baseline, six, twelve, eighteen and twent...

From the Departments of Neurology and Pathology, Cornell University Medical College, New York, N. 1. Supported in part by Research Grants HE-04872 and NB-03346, NB-04161 from USPHS and from the Winthrop Laboratories. Dr. Kutt is a recipient of a Research Career Development Award JKO 3 NB 35003, NINDB, USPH. First submitted October 2, 1968; accepted for publication December 13, 1968. KARL VEREBE...