نتایج جستجو برای: نظریه منطقه بهینه پولی oca
تعداد نتایج: 144106 فیلتر نتایج به سال:
Epidemiological data have implicated reproductive hormones as probable risk factors for ovarian cancer (OCa) development. Although pituitary and sex hormones have been reported to regulate OCa cell growth, no information is available regarding whether and how they influence normal ovarian surface epithelial (OSE) cell proliferation. To fill this data gap, this study has compared cell growth res...
BACKGROUND Oculocutaneous albinism (OCA) is the most common inherited disorder in Southern African blacks and several types have been described. Molecular techniques, where available, can be used to confirm a clinical diagnosis and the type of OCA, if necessary, and for prenatal diagnosis. OBJECTIVES To investigate and classify the different types of albinism commonly found and to determine t...
BACKGROUND & AIMS Options for the prevention of short-bowel syndrome-associated liver disease (SBS-ALDs) are limited and often ineffective. The farnesoid X receptor (FXR) is a newly emerging pharmaceutical target and FXR agonists have been shown to ameliorate cholestasis and metabolic disorders. The aim of this study was to assess the efficacy of obeticholic acid (OCA) treatment in preventing S...
BACKGROUND Fresh osteochondral allograft (OCA) transplantation is an effective treatment for osteochondral defects. Some patients require further surgical intervention, such as total knee arthroplasty (TKA). The effects of prior OCA transplantation on TKA outcomes are unknown. PURPOSE This study evaluated TKA failure rates after long-term follow-up and identified factors that may have contrib...
Farnesoid X receptor (FXR) is a master regulator of bile acid homeostasis through transcriptional regulation of genes involved in bile acid synthesis and cellular membrane transport. Impairment of bile acid efflux due to cholangiopathies results in chronic cholestasis leading to abnormal elevation of intrahepatic and systemic bile acid levels. Obeticholic acid (OCA) is a potent and selective FX...
Photodynamic therapy (PDT) is a promising modern approach for cancer therapy with low normal tissue toxicity. This study was focused on a vascular-targeting Chlorine E6 mediated PDT. A new angiographic imaging approach known as M-mode-like optical coherence angiography (MML-OCA) was able to sensitively detect PDT-induced microvascular alterations in the mouse ear tumour model CT26. Histological...
We have isolated and functionally characterized a multicomponent Oct-1 coactivator, OCA-S which is essential for S phase-dependent histone H2B transcription. The p38 component of OCA-S binds directly to Oct-1, exhibits potent transactivation potential, is selectively recruited to the H2B promoter in S phase, and is essential for S phase-specific H2B transcription in vivo and in vitro. Surprisin...
هدف این مقاله محاسبه رفاه تحت سیاست های مالی متفاوت با استفاده از یک مدل تعادل عمومی تصادفی پویا در چارچوب سیاست پولی و مالی بهینه برای اقتصاد ایران می باشد. برای بررسی اثرات به کارگیری ابزارهای مالیاتی سناریوهای مختلفی ارائه می شود. نتایج نشان داد تعداد و نوع ابزارهای سیاست مالی در دسترس برنامه ریزنقش مهمی درتعیین میزان تغییرات رفاه در یک مدل سیاست پولی و مالی بهینه، ایفا می کند. پیشنهاد می شو...
در این مقاله،هدف بررسی اثرات ناشی از تغییرات پویایی متغیرهای کنترل دولت بر روی متغیرهای بورس اوراق بهادار ایران با استفاده از نظریه کنترل بهینه است. بر این اساس سعی شده تا در قالب این نظریه، مسیرهای بهینه متغیرهای کنترل؛ نظیر حجم پول، نرخ ارز، مالیاتها و مخارج دولت و متغیرهای حالت؛ مانند ارزش بازاری سهام و حجم معاملات، طی برنامه سوم و چهارم توسعه تعیین شود. ابتدا بر پایه مطالعات قبلی و همچنین م...
We evaluated a 32-year-old woman whose oculocutaneous albinism (OCA), bleeding diathesis, neutropenia, and history of recurrent infections prompted consideration of the diagnosis of Hermansky-Pudlak syndrome type 2. This was ruled out because of the presence of platelet δ-granules and absence of AP3B1 mutations. As parental consanguinity suggested an autosomal recessive mode of inheritance, we ...
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