BACKGROUND The optimal treatment method of T1 glottic squamous cell carcinoma (SCC) with involvement of the anterior commissure is still debatable. We compared the outcomes of radiotherapy (RT) and transoral laser microsurgery (TLM). METHODS Data were retrospectively collected for 54 patients who were treated by RT (n = 38) or TLM (n = 16) from 2006 to 2013. RESULTS No between-group differe...

To investigate the effect of surface nanostructures on the behaviors of human umbilical vein endothelial cells (HUVECs), surface nanostructured titanium alloy (Ti-3Zr2Sn-3Mo-25Nb, TLM) was fabricated by surface mechanical attrition treatment (SMAT) technique. Field emission scanning electron microscopy (FE-SEM), atomic force microscopy (AFM), transmission electron microscopy (TEM) and X-ray dif...

Introduction Transoral laser microsurgery (TLM) has established itself as an effective option in the management of malignant tumors of the glottis, supraglottis, and hypopharynx. Nonetheless, TLM is not a harmless technique. Complications such as bleeding, dyspnea, or ignition of the air may appear in this type of surgery. Objective The aim of this study is to describe the complications that oc...

BACKGROUND In this study, we established a hypothetical tumor-lodds-metastasis (TLM) and tumor-ratio-metastasis (TRM) staging system. Moreover, we compared them with the 7(th) edition of American Joint Committee on Cancer tumor-nodes-metastasis (AJCC TNM) staging system in gastric cancer patients after D2 resection. METHODS A total of 1000 gastric carcinoma patients receiving treatment in our...

The development of embedded systems starts more and more by the design of abstract models written in SystemC/TLM [18, 6]. These models allow the simulation of the embedded software before the hardware RTL descriptions are available, and are used as golden models for hardware verification. The verification of the SystemC/TLM models is an important issue, since a error in the model can mislead th...

We present a methodology for design of complex digital systems at system level through a training video. After the introduction to SystemC and TLM-2.0, the video explains a number of design sub-levels and guidelines for design at each sub-level. A test data compression system is implemented as a case study using OSCI TLM 2.0 standard. .

Chromatographic separation and detection of nonfluorescent molecules were integrated in a nanochannel. Our method, extended-nano chromatography realized high-performance separation using pressure-driven flow in a 100-nm scale nanochannel. A photothermal detector, differential interference contrast thermal lens microscope (DIC-TLM) was employed for detection of nonfluorescent samples. In particu...

OBJECTIVE The optimal treatment strategy for oropharyngeal squamous cell carcinoma is highly debated. However, growing evidence supports the use of minimally invasive techniques, such as transoral laser microsurgery (TLM), as a first-line treatment modality for these carcinomas. The purpose of our study was to assess the efficacy and safety of TLM for the treatment of primary and recurrent orop...

In this paper, we evaluate the effectiveness of model slicing to provide assurance about correctness of SystemC TLM programs. The need for such assurance is important since SystemC has become a de-facto standard for building systems with hardware/software co-design. Existing approaches that enable one to transform the given SystemC TLM program into an UPPAAL model that can be verified suffer fr...

BACKGROUND We conducted longitudinal voice evaluations in patients with early glottic cancer who underwent transoral laser microsurgery (TLM) to determine the time to stability. METHODS Twenty-five patients underwent TLM, including 13 limited cordectomies (type I and type II) and 12 extended cordectomies (type III to type IV). Multidimensional voice evaluations were performed before treatment...