نتایج جستجو برای: پروتئین p0
تعداد نتایج: 21401 فیلتر نتایج به سال:
In this paper, we consider an infinite dimensional exponential family P of probability densities, which are parametrized by functions in a reproducing kernel Hilbert space H, and show it to be quite rich in the sense that a broad class of densities on R can be approximated arbitrarily well in Kullback-Leibler (KL) divergence by elements in P. Motivated by this approximation property, the paper ...
We introduce bidiagonal coordinates, a new set of spectral coordinates on open dense charts covering the space of real symmetric tridiagonal matrices. In contrast to the standard Jacobi inverse variables, reduced tridiagonal matrices now lie in the interior of some chart. Bidiagonal coordinates are thus convenient for the study of asymptotics of isospectral dynamics, both for continuous and dis...
Mutations in the genes for peripheral myelin protein-22 (PMP22) and myelin protein zero (P0) cause human hereditary neuropathies with varying clinical and pathological phenotypes. In this study, we examine the effects of representative disease-causing mutations on the subcellular distribution of their corresponding PMP22- and P0-enhanced green fluorescent protein (EGFP) fusion proteins. In tran...
Point mutations in the cytoplasmic domain of myelin protein zero (P0; the major myelin protein in the peripheral nervous system) that alter a protein kinase Calpha (PKCalpha) substrate motif (198HRSTK201) or alter serines 199 and/or 204 eliminate P0-mediated adhesion. Mutation in the PKCalpha substrate motif (R198S) also causes a form of inherited peripheral neuropathy (Charcot Marie Tooth dise...
Let X0 be an irreducible projective nodal curve with only one singular point, and let P0 be a line bundle on X0. The moduli SUX0(r;P0) of rank r vector bundles on X0 with determinant P0 is not compact. In [A], using the technique of Kausz ([K1], [K2]), we constructed a compactification GSL2B(X0;P0) of SUX0(2;P0), and studied its structure. Surprisingly, despite its seemingly natural definition,...
If ≤ is a preorder on a set P and p0 ≤ p1, we say that p1 is an extension of p0. Recall that a preorder is separative if and only if whenever p1 is not an extension of p0 there is an extension of p1 which is incompatible with p0. We say that P = (P,≤) is a forcing notion (also forcing poset) if ≤ is a separative preorder with minimal element 0P. Note that if P is separative and p1 p̌0 ∈ Ġ then p...
Let L be a linear space of real bounded random variables on the probability space (Ω,A, P0). There is a finitely additive probability P on A, such that P ∼ P0 and EP (X) = 0 for all X ∈ L, if and only if c EQ(X) ≤ ess sup(−X), X ∈ L, for some constant c > 0 and (countably additive) probability Q on A such that Q ∼ P0. A necessary condition for such a P to exist is L − L+∞ ∩ L + ∞ = {0}, where t...
“The NURBS Book” [L. Piegl, W. Tiller, The NURBS Book, second edn, Springer, 1997] is very popular in the fields of computer aided geometric design (CAGD) and geometric modeling. In Section 9.5.2 of the book, the well-known problem of the local cubic spline approximation is discussed. The key in local cubic spline approximation is cubic polynomial interpolation. In this short paper, we present ...
A typical feature in systemic lupus erythemathosus patients is the presence of autoantibodies to the carboxyl-terminal homologous P proteins (P0, P1, P2) domain (C-22 P0 epitope). In this report we provide evidence for the in vivo immunogenicity of the P0 protein in head and neck cancer patients as well as overexpression by immunohistochemistry of the C-22 P0 epitope in invasive carcinomas (55/...
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