Apoptosis-linked gene-2 (ALG-2) encodes a 22 kDa Ca(2+)-binding protein of the penta EF-hand family that is required for programmed cell death in response to various apoptotic agents. Here, we demonstrate that ALG-2 mRNA and protein are down-regulated in human uveal melanoma cells compared to their progenitor cells, normal melanocytes. The down regulation of ALG-2 may provide melanoma cells wit...

In this paper, we first characterize reflexive one-sided A -submodules U of a unital operator algebra A in B(H ) completely. Furthermore we investigate the invariant subspace lattice Lat R and the reflexive hull Ref R, where R is the submodule generated by rank-one operators in U ; in particular, if L is a subspace lattice, we obtain when the rank-one algebra R of Alg L is big enough to determi...

We consider algorithms for learning functions f : X ! Y , where X and Y are nite, and there is assumed to be no noise in the data. Learning algorithms, Alg, are connected with ?(Alg), the set of prior probability distributions for which they are optimal. A method for constructing ?(Alg) from Alg is given and the relationship between the various ?(Alg) is discussed. Improper algorithms are ident...

abstract background: lymphoproliferative disorders are among the most serious and potentially fatal complications of chronic immunosuppression in kidney transplant recipients. the principle risk factors for development of ptld are the degree of overall immunosuppression and the ebv serostatus of the recipient. in this study, the risk of ptld in kidney transplant recipients who received anti- ly...

Purpose. The antitumor activity of a novel alginate (ALG) polymer-based particle that contained paclitaxel (PTX) was evaluated using human primary breast cancer cells. Materials and Methods. PTX was combined with ALG in a nanoparticle as a drug delivery system designed to improve breast cancer tumor cell killing. PTX-ALG nanoparticles were first synthesized by nanoemulsification polymer cross-l...

Afetleri önlemek ve afetlerin zararlar?n? azaltmak için birçok yap?sal olmayan çal??ma yürütülmektedir. Özellikle afetler olas? sonuçlar? hakk?nda insanlar?n dü?üncelerini anlamak afet risk azaltma çal??malar? önemlidir. Çünkü, dü?ünceleri afetlere kar?? koruyucu önlem alma davran??lar?n? etkilemektedir. Bu çal??man?n amac?, afetlerle ilgili yürütülen bilimsel alg?s? çal??malar?n?n yönetimi aç?...

A new microsphere consisting of inorganic mesoporous silica nanoparticles (MSNs) and organic alginate (denoted as MSN@Alg) was successfully synthesized by air-dynamic atomization and applied to the intracellular drug delivery systems (DDS) of liver cancer cells with sustained release and specific targeting properties. MSN@Alg microspheres have the advantages of MSN and alginate, where MSN provi...

Suppose that independent U 0 1 weights are assigned to the (d2)n2 edges of the complete d-partite graph with n vertices in each of the d = maximal independent sets. Then the expected weight of the minimum-weight perfect d-dimensional matching is at least 3 16n 1− 2/d . We describe a randomized algorithm that finds a perfect d-dimensional matching whose expected weight is at most 5d3n1− 2/d + d1...

In this study, 2-[(Acryloyloxy)ethyl]trimethylammonium chloride was graft polymerized onto chitosan (CS) to form quaternary ammonium CS (QAC) by using ammonium persulfate as a redox initiator. Alginate (ALG) microspheres loaded with a water-soluble macromolecular model drug, blue dextran (BD), were obtained by corporation of coaxial gas-flow method and ionic gelation process. CS and QAC were th...

The specificity of anti-lymphocyte globulin (ALG) has been used to analyze an immune mechanism which is mediated by immunologically committed lymphoid cells to the apparent exclusion of humoral antibody. Rabbit antimouse lymphocyte globulin completely suppressed the immunity which can be passively transferred with Listeria-immune lymphoid cells from actively infected donors. When prospective do...