Asynchronous Transfer Mode (ATM) technology performance is evaluated for Class C (variable bit rate, asynchronous) data transfer, as would be typically found when migrating legacy applications to an ATM environment. Of particular interest are the end-to-end latencies obtainable using ATM networks to transfer time critical data. Latencies obtained using Classical IP over ATM and raw ATM using th...

10 µm lasing is studied in a compact CO 2 -He cell pressurized up to 15 atm when optically pumped by ∼50 mJ Fe:ZnSe laser tunable around 4.3 µm. The optimal pump wavelength and partial pressure of for generating pulses are found be ∼4.4 0.75 atm, respectively. Without cavity optimization, the optical-to-optical conversion efficiency reached ∼10% at total 7 atm. gain lifetime measured ∼1 µs pres...

Ataxia telangiectasia (A-T) mutated (ATM) kinase orchestrates deoxyribonucleic acid (DNA) damage responses by phosphorylating numerous substrates implicated in DNA repair and cell cycle checkpoint activation. A-T patients and mouse models that express no ATM protein undergo normal embryonic development but exhibit pleiotropic DNA repair defects. In this paper, we report that mice carrying homoz...

This report shows several videoconferencing services offered by the Advanced Broadband Communications Centre (C.CABA) of the Universitat Politècnica de Catalunya. These services are provided thanks to a high performance CSCW application (ISABEL). Moreover, all these activities used ATM as Wide Area Network technology, through the Spanish ATM Network (GIGACOM).

ATM has a central role in controlling the cellular responses to DNA damage. It and other phosphoinositide 3-kinase-related kinases (PIKKs) have giant helical HEAT repeat domains in their amino-terminal regions. The functions of these domains in PIKKs are not well understood. ATM activation in response to DNA damage appears to be regulated by the Mre11-Rad50-Nbs1 (MRN) complex, although the exac...

x-ATM is a portable toolkit of Asynchronous Transfer Mode (ATM) protocols implemented in a general purpose communications kernel (the x-kernel). The toolkit provides an environment for experimentation with ATM adaptation layers, interoperable ATM signalling, IP over ATM, and real time transport protocols. The x-kernel permits easy composability and promotes protocol modularity, thus x-ATM proto...

The Atm protein kinase is central to the DNA double-strand break response in mammalian cells. After irradiation, dimeric Atm undergoes autophosphorylation at Ser 1981 and dissociates into active monomers. Atm activation is stimulated by expression of the Mre11/Rad50/nibrin complex. Previously, we showed that a C-terminal fragment of nibrin, containing binding sites for both Mre11 and Atm, was s...