BACKGROUND/AIMS Moisturising creams are useful treatment adjuncts in inflammatory dermatoses and have beneficial effects in the treatment of dry, scaly skin. The effects on dryness and skin permeability of a new moisturising cream with 20% glycerine was compared with its placebo and with a medicinally authorised cream with 4% urea (combined with 4% sodium chloride) in the treatment of dry skin....

Oleum Hyperici, the oil extract of St. John's Wort (SJW), is one of the oldest folk remedies, traditionally used in the topical treatment of wounds, bruises, ulcers, cuts, burns, hemorrhoids and also as an antiseptic. Considering the advantageous characteristics of emulsion applications, in the present study we have formulated three O/W creams containing 15% (w/v) of SJW oil extract as an activ...

Pressure ulcers are common among selected patient populations. Early therapeutic intervention may result in a decrease in the number of ulcers that progress to a later stage. The efficacy of specific skin creams for the treatment and prevention of early stage pressure ulcers has not previously been evaluated. We compared the healing rates of paired, early stage pressure ulcers treated with eith...

Outcome Measures Parentor child-rated severity of itch; parentor child-rated severity of sleep disturbance, irritability and skin appearance; emollient use (adherence); attitudes to eczema and emollient therapy. Results 50 subjects completed the intervention and follow-up. 20% had previously been shown how to apply emollient creams by a GP or nurse but only 10% were applying them correctly. The...

Treatment of neuropathic pain using topical formulations is still in its infancy. Only few topical analgesic formulations have become available for clinical use, and among these, analgesic creams are still rare. This is unfortunate because analgesic creams offer a number of advantages over patches, such as convenience, ease of adapting the frequency of application, and dose, and "rubbing cream ...

BACKGROUND Irritant contact dermatitis (ICD) from repetitive hand hygiene is the primary reason for compliance failure among health care workers (HCWs). Chronic ICD has implications for infection control because higher bacterial counts are associated with increased skin compromise. Guidelines recommend lotions/creams to lessen irritation. We evaluated the effects of 5 to 10 daily applications o...