The "enhanced intracellular survival" (eis) gene of Mycobacterium tuberculosis (Mtb) is involved in the intracellular survival of M. smegmatis. However, its exact effects on host cell function remain elusive. We herein report that Mtb Eis plays essential roles in modulating macrophage autophagy, inflammatory responses, and cell death via a reactive oxygen species (ROS)-dependent pathway. Macrop...

Background According to the World Health Organization, the use of Electronic Information Sources (EIS) in healthcare is not merely about application of technology, but it is also a foundation to provide higher quality clinical care. This study was aimed to assess Utilization Status of EIS for HIV/AIDS Care and Treatment in specialized teaching hospitals of Ethiopia, 2016. Materials and Method...

To further understand Mycobacterium tuberculosis pathogenesis, the regulation of potential virulence genes needs to be investigated. The eis gene of M. tuberculosis H37Rv enhances the intracellular survival of Mycobacterium smegmatis, which does not contain eis, within macrophages (J. Wei, J. L. Dahl, J. W. Moulder, E. A. Roberts, P. O'Gaora, D. B. Young, and R. L. Friedman, J. Bacteriol. 182:3...

In recent years, a number of organisations have invested heavily in executive information systems (EIS) in order to improve the performance gains of their executives’ roles. Although executives presided over and authorised investment in EIS projects to support their roles, the majority of executives are unenthusiastic about using EIS because of the design flaws and failures of these systems. St...

The success of an executive information system (EIS) depends upon many factors, including providing support for the strategic management process (SMP). The SMP is comprised of five phases: organizational objectives, environmental scanning, strategy formulation, strategy implementation, and strategic control. The study empirically investigated (1) the support of EISs for the phases of the SMP an...

Although there have been a number of studies on large scale implementation of proprietary enterprise information systems (EIS), open-source software (OSS) for EIS has received limited attention in spite of its potential as a disruptive innovation. Cost saving is the main driver for adopting OSS among the other possible benefits including security and reliability, transparency of development pro...

There is growing evidence that strains of Mycobacterium tuberculosis differ in pathogenicity and transmissibility, but little is understood about the contributory factors. We have previously shown that increased expression of the principal sigma factor, SigA, mediates the capacity of M. tuberculosis strain 210 to grow more rapidly in human monocytes, compared with other strains. Strain 210 is p...

Electrical Impedance Spectroscopy (EIS) has emerged as a non-invasive imaging modality to detect and quantify functional or electrical properties related to the suspicious tumors in cancer screening, diagnosis and prognosis assessment. A constraint on EIS systems is that the current excitation system suffers from the effects of stray capacitance having a major impact on the hardware subsystem a...

Electrochemical impedance spectroscopy (EIS) has been used to estimate the non-frequency dependent (static) dielectric constants of base polymers such as poly(vinyl chloride) (PVC), cellulose triacetate (CTA) and polystyrene (PS). Polymer inclusion membranes (PIMs) containing different amounts of PVC or CTA, along with the room temperature ionic liquid Aliquat 336 and plasticizers such as trisb...

This paper shows that the CRRA specification of intertemporal preferences (implying a constant elasticity of intertemporal substitution, or EIS), imposes surprising limitations on within period budget allocations. Consequently, the constant EIS assumption can be tested with demand data. In fact, the parameter of the CRRA utility function is pinned down completely by the shape of Engel curves; i...