OBJECTIVE Genotyping for CYP2D6 has the potential to predict differences in metabolism of nortriptyline. This information could optimize pharmacotherapy. We determined the costs and effects of routine genotyping for old aged Dutch depressed inpatients. METHODS With a decision-tree, we modelled the first 12 weeks of nortriptyline therapy. Direct costs of genotyping, hospitalization, therapeuti...

The Brazilian response to AIDS started in 1985, with government, civil society and academic community coming together with common goals. This was strengthened with the establishment in 1988 of an universal public health system (SUS), pivotal to a comprehensive and human rights-based national STD/AIDS programme, aiming at achieving equality, integrality, inclusion and fighting prejudice and disc...

Ensuring treatment adherence is critical for the success of ART programs in developing countries. Enlisting NGOs or PLHA group members as treatment supporters is one common strategy. Less attention is given to family members and especially older-age parents. Yet ART patients often live with other family members who are highly motivated to ensure treatment success. This study examines the role o...

East Asia is a very integral region, the Asian sub-kingdom of Holarctic, in which two large areas stand out: Sino-Himalayan and Sino-Japanese. The flora rich unique. About 25 000 species vascular plants grow this area. There are about 23 endemic families over 350 genera. number 15 000. In Asia, there modern centers diversity for many plants, but also relict groups that have survived territory f...

The copper(II) complex [Cu(pic)2]·2H2O was synthesized with 2-picolinic acid (Hpic) and copper acetate as reactants by room temperature solid-solid reaction. The composition and structure of the complex was characterized by elemental analyses, single crystal X-ray diffraction, X-ray powder diffraction, FT-IR spectroscopy and thermogravimetry-differential scanning calor...

BACKGROUND Despite its importance in HIV/AIDS prevention and treatment, HIV/AIDS Counseling and Testing (HCT) is low in sub-Saharan Africa, where the disease continues to be a serious public health problem. This has in part been attributed to HIV/AIDS related stigma. OBJECTIVE To assess the level of HIV/AIDS related stigma and its impact on uptake of HCT in a high HIV prevalence population in...