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Introduction The most serious complication in Familial Mediterranean fever (FMF) is the development of amyloidosis, which usually determines the prognosis. Amyloid deposition can be systemic or organ-specific. The clinical features of amyloidosis are dependent on the organs involved, type of amyloidosis, rate of amyloid deposition and amount of amyloid fibrils. Organ dysfunction can cause life-...
A Gram-stain-positive, rod-shaped, non-endospore-forming, orange-pigmented (coloured) actinobacterium (01-Je-003(T)) was isolated from the wall of an indoor environment primarily colonized with moulds. On the basis of 16S rRNA gene sequence similarity studies, strain 01-Je-003(T) was shown to belong to the genus Brevibacterium and was most similar to the type strains of Brevibacterium picturae ...
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy, with most patients facing an adverse clinical outcome. Aberrant Notch pathway activation has been implicated in the initiation and progression of PDAC, specifically the aggressive phenotype of the disease. We used a panel of human PDAC cell lines as well as patient-derived PDAC xenografts to determine whether pharmacologic targetin...
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy, with most patients facing an adverse clinical outcome. Aberrant Notch pathway activation has been implicated in the initiation and progression of PDAC, specifically the aggressive phenotype of the disease. We used a panel of human PDAC cell lines as well as patient-derived PDAC xenografts to determine whether pharmacologic targetin...
Abstract The crystal plane plays a very important role in the properties of Ni‐rich cathodes. [003] crystallographic texture regulation has been proven to improve structural stability, and yet, discrepancy particles with different exposed ratios attenuation not clarified. Herein, we have unraveled comprehensively decay difference for cathodes’ primary percentages by regulating precursor copreci...
Results In our cohort (148 males and 120 females) fever began at 26.2 + 24 months of age. 8% of the patients had an onset after the fifth year of life, but all other Thomas criteria were met. A family history was present in 39.6% of patients. Mean duration of PFAPA episodes was 4 + 1.6 days, and a mean interval between episodes 27.9 + 11 days. Most common symptoms with fever were pharyngitis (9...
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