نتایج جستجو برای: 0081

تعداد نتایج: 104  

2002
D. N. Haylock T. Dowse P. J. Simmons

Peripheral blood (PB) CD34+ cells from four commonly used mobilization protocols were studied to compare their phenotype and proliferative capacity with steady-state PB or bone marrow (BM) CD34' cells. Mobilized PB CD34+ cells were collected during hematopoietic recovery after myelosuppressive chemotherapy with or without granulocytemacrophage colony-stimulating factor (GM-CSF) or granulocyte c...

2014
Quentin S. Hanley Suniya Khatun Amal Yosef Rachel-May Dyer Rachata Muneepeerakul

Fluctuation scaling relationships have been observed in a wide range of processes ranging from internet router traffic to measles cases. Taylor's law is one such scaling relationship and has been widely applied in ecology to understand communities including trees, birds, human populations, and insects. We show that monthly crime reports in the UK show complex fluctuation scaling which can be ap...

2014

The recent recognition that acute kidney injury (AKI) may lead to the development of chronic kidney disease and endstage renal disease, with the attendant increase in mortality, has led to interest in the clinical epidemiology and the mechanistic understanding of renal recovery after an episode of AKI. At present, no uniform definition for recovery after AKI exists and various considerations sh...

Journal: :Blood 2012
Filip Callewaert Jan Roodt Hans Ulrichts Thomas Stohr Walter Janse van Rensburg Seb Lamprecht Stefaan Rossenu Sofie Priem Wouter Willems Josefin-Beate Holz

ALX-0681 is a therapeutic Nanobody targeting the A1-domain of VWF. It inhibits the interaction between ultra-large VWF and platelet GpIb-IX-V, which plays a crucial role in the pathogenesis of thrombotic thrombocytopenic purpura (TTP). In the present study, we report the efficacy and safety profile of ALX-0681 in a baboon model of acquired TTP. In this model, acute episodes of TTP are induced b...

2013
Marie-Hélène Lafeuille François Laliberté-Auger Patrick Lefebvre Christian Frois John Fastenau Mei Sheng Duh

BACKGROUND Among schizophrenia patients relapsed on an oral antipsychotic (AP), this study compared the impact of switching to atypical AP long-acting injectable therapy (LAT) versus continuing oral APs on hospitalization and emergency room (ER) visit recurrence. METHODS Electronic records from the Premier Hospital Database (2006-2010) were analyzed. Adult patients receiving oral APs during a...

اسمعیل قهرمانی محمد علی ززولی مهدی قربانیان اله آباد پگاه بهمنی کبری ذبیح زاده

ا توجه به سرطانزایی و سایر خطرات بهداشتی نیترات و نیتریت در آبهای آشامیدنی این مطالعه با هدف بررسی غلظت اینب یونها در آبچاه روستاهای شهرستان ساری در سالهای 1386و 1387و مقایسه مقدار آنها با سطوح استاندارد ایران انجام شده است. در این تحقیق، 152نمونه آب در هر سال از 38مجتمع آبرسانی روستاهای شهرستان ساری که آب آنها از چاه تامین میگردد مورد بررسی قرار گرفت. غلظتیونهای نیترات و نیتریت توسط دستگاه اسپ...

در دستیابی به معیشت پایدار روستایی شناخت دقیق و کامل عوامل مؤثر بر فرآیند شکل­گیری و توسعه مناطق روستایی ضرورت دارد. در این راستا شناسایی و ارزیابی معیارها و شاخص­های پایداری معیشت روستایی می­تواند راهگشا باشد. در این مطالعه سعی بر آن شد از طریق بررسی منابع کتابخانه­ای و سوابق مطالعاتی موجود معیارها و شاخص­های معیشت پایدار روستایی ایران شناسایی و مورد ارزیابی قرار گیرند تا با اولویت­بندی آن بتو...

2013
Yvonne Kienast Christian Klein Werner Scheuer Romi Raemsch Erica Lorenzon Dirk Bernicke Frank Herting Sidney Yu Huynh Hung The Laurent Martarello Christian Gassner Kay-Gunnar Stubenrauch Kate Munro Hellmut G. Augustin Markus Thomas

Purpose:VEGF-A blockade has been clinically validated as a treatment for human cancers. Angiopoietin2 (Ang-2) expression has been shown to function as a key regulator of tumor angiogenesis and metastasis. Experimental Design:We have applied the recently developed CrossMab technology for the generation of a bispecific antibody recognizing VEGF-A with one arm based on bevacizumab (Avastin), and t...

Journal: :AJNR. American journal of neuroradiology 2014
P M Mostardi F E Diehn J B Rykken L J Eckel K M Schwartz T J Kaufmann C P Wood J T Wald C H Hunt

BACKGROUND AND PURPOSE Studies systematically evaluating the detection of intramedullary spinal cord metastasis with PET are lacking. Our purpose was to evaluate the visibility of intramedullary spinal cord metastasis on PET in a single institutional series and to correlate PET and MR imaging features. MATERIALS AND METHODS Patients were included if pretreatment MR imaging identifying an intr...

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