“Think globally; act locally.” This bumper sticker maxim has a lot to say to practitioners of contemporary high performance computing. It is increasingly incumbent on computational scientists to respect the data access hierarchies that accompany the large memories required by applications programs. These hierarchies are imposed, ultimately, by the finite size of data storage media and the finit...

Pancreatoduodenectomy is now the most fundamental operation for cancer of the pancreatic head. However, with the conventional operative procedure, the resection rate is low and long-term results are extremely poor. We introduced an extended radical Whipple operation in 1978 to improve surgical curability. Systemic dissection of extended lymph nodes and plexuses and en bloc resection of the port...

Objective: In order to determine the optimal surgical strategy for acute ascending aortic dissection, the graft inclusion technique was compared with the open resection technique. Methods: Between 1985 and 1995 a consecutive series of 193 patients (77% male, mean age 58 years) had emergency surgery during a mean interval of 13.2 h after onset of symptoms. Graft replacement of the ascending aort...

Agreement problems involve a system of processes, some of which may be faulty. A fundamental problem of fault-tolerant distributed computing is for the reliable processes to reach a consensus. We survey the considerable literature on this problem that has developed over the past few years and give an informal overview of the major theoretical results in the area. 1. A g r e e m e n t P r o b l ...

doi:10.3415/VCOT-12-12-0154 Our first issue of VCOT for this year contains several papers pertaining to the study of fracture morphology, and the stabilization of fractures with bone plates (1-3). In addition, Herten and colleagues describe the characterization of mesenchymal stem cells isolated from bone marrow by a point-of-care device; these cells had osteogenic potential that could be expec...

doi:10.3415/VCOT-12-12-0154 Our first issue of VCOT for this year contains several papers pertaining to the study of fracture morphology, and the stabilization of fractures with bone plates (1-3). In addition, Herten and colleagues describe the characterization of mesenchymal stem cells isolated from bone marrow by a point-of-care device; these cells had osteogenic potential that could be expec...

Corrections are given to some of the proofs of the paper above In this note, we point out and correct some errors in the proofs of the main results in the paper [1]. The main results themselves are correct as stated, but the proofs need modification. To begin, the proof of Lemma 3.3 in [1] is incorrect. Thus, h in [1, (3.12)] is the linearization of a mapping ∂C → ∂C, and so has n degrees of fr...

doi:10.3415/VCOT-12-12-0154 Our first issue of VCOT for this year contains several papers pertaining to the study of fracture morphology, and the stabilization of fractures with bone plates (1-3). In addition, Herten and colleagues describe the characterization of mesenchymal stem cells isolated from bone marrow by a point-of-care device; these cells had osteogenic potential that could be expec...

Presynaptic GABA B receptors (GABA B R) control glutamate and GABA release at many synapses in the nervous system. In the present study we used whole-cell patch-clamp recordings of spontaneous excitatory and inhibitory synaptic currents in the presence of TTX to monitor glutamate and GABA release from synapses in layer II and V of the rat entorhinal cortex (EC) in vitro. In both layers the rele...