BACKGROUND Durable HIV-1 remission after interruption of combined antiretroviral therapy (ART) has been reported in some adults who started treatment during primary infection; however, whether long-term remission in vertically infected children is possible was unknown. We report a case of a young adult perinatally infected with HIV-1 with viral remission despite long-term treatment interruption...

HLA-A2 is the most frequent HLA-A allele in all ethnic populations, and an important restriction element for peptide presentation to T cells in infectious disease and cancer. However, the HLA-A2 supertype consisting of up to 75 subtypes, mutation studies and analyses using cytotoxic T lymphocytes suggest the functional relevance of subtype-specific differences in HLA-A2 molecules for peptide bi...

Spatio-temporal statistical models are increasingly being used across a wide variety of scientific disciplines to describe and predict spatially-explicit processes that evolve over time. Correspondingly, in recent years there has been a significant amount of research on new statistical methodology for such models. Although descriptive models that approach the problem from the second-order (cova...

Santos, A. 2018. Hemodynamic Effects of Lung Function Optimization in Experimental Acute Respiratory Distress Syndrome. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1419. 60 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0210-2. Acute Respiratory Distress Syndrome (ARDS) is a severe pulmonary inflammation affecting thousands of patients eve...

1 D e f i n i t i o n s Given a graph G, let V(G) be the set of vertices of G, E(G) the set of edges of G. For A, B subsets of V(G), let E(A) be the set of edges of G with both ends in A, and let E(A, B) be the set of edges of G with one end in A, the other in B. A map M on a surface S is a connected graph G toge~..her with a 2-cell embedding of G in S. Two maps are equivalent if there is a hom...

Recent results from our laboratory,'-3 as well as data reported by others,4' have shown that gastroduodenal blood flow functions not only provide 0210 and substrates, but also deliver HCO3 to the mucosa. This may be of particular relevance to the pathogenesis of stress ulceration. Sepsis and haemorrhagic shock are frequently associated with systemic acidosis and reduced arterial HCO3 concentrat...

We report IRAM millimeter interferometry of three –3.4 Submillimeter Common-User Bolometric Array z ∼ 2.4 deep field galaxies. Our CO line observations confirm the rest-frame UV/optical redshifts, thus more than doubling the number of confirmed published redshifts of the faint submillimeter population and proving their high-z nature. In all three sources our measurements of the intrinsic gas an...

The construction of exact exponential-time algorithms for NP-complete problems has for some time been a very active research area. Unfortunately, there is a lack of general methods for studying and comparing the time complexity of algorithms for such problems. We propose such a method based on clone theory and demonstrate it on the SAT problem. Schaefer has completely classi ed the complexity o...