Introduction Robert Sweet first described a syndrome with a painful, erythematous nodular plaques, neutrophilic dermal infiltrates, fevers and peripheral neutrophilia. This cluster of syndromes became known as Sweet’s syndrome. There have been many published cases in children of neutrophilic dermatoses and fever which are labeled as Sweet’s syndrome. Recently, however, neutrophilic dermatoses h...

1 Department of Medicine, Jawaharlal Nehru Medical College, Sawangi, Meghe-440 022, Maharashtra, India. 2 Department of Pediatrics, Jawaharlal Nehru Medical College, Sawangi, Meghe-440 022, Maharashtra, India. 3 Department of Medicine, Jawaharlal Nehru Medical College, Sawangi, Meghe-440 022, Maharashtra, India. [email protected] Abstract Diabetic polyneuropathy is one of the more comm...

The geldanamycin derivative 17-allylamino-17-demethoxygeldanamycin (17-AAG) is known to induce internalisation and degradation of the otherwise internalisation-resistant human epidermal growth factor receptor 2 (HER2) receptor. In the present study, 17-AAG was used to increase internalisation of the HER2-specific Affibody molecule ABY-025. The cellular redistribution of halogen-labelled 211At-A...

OBJECTIVES To examine trends in social and geographic inequalities in all-cause premature adult mortality in Japan. DESIGN Observational study of the vital statistics and the census data. SETTING Japan. PARTICIPANTS Entire population aged 25 years or older and less than 65 years in 1970, 1975, 1980, 1985, 1990, 1995, 2000 and 2005. The total number of decedents was 984 022 and 532 223 in ...

PURPOSE Positron Emission Tomography (PET) imaging of HER2 expression could potentially be used to select patients for HER2-targed therapy, predict response based on uptake and be used for monitoring. In this phase I/II study the HER2-binding Affibody molecule ABY-025 was labeled with (68)Ga-gallium ([(68)Ga]ABY-025) for PET to study effect of peptide mass, test-retest variability and correlati...

Introduction The cytoplasmic S100 proteins derived from cells of myeloid origin. Calprotectin (MRP8/14 protein complex) might be a biomarker either for autoinflammation and autoimmunopathy. Since autoinflammatory diseases might be a diagnostic challenge calprotectin may be helpful in the diagnosis of autoinflammatory diseases. Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory, non...

The adults of Calochromini with male flabellate antennae were studied. Two new Calochromus Guérin-Méneville, 1833 species with flabellate antennae, C. kelantanensis spec. nov. and C. harauensis spec. nov. are described. Dumbrellia Lea, 1909 (Calochromini) is proposed as a new junior synonym of Plateros Bourgeois, 1879 (Lycinae: Platerodini). Flabellochromus Pic, 1925 is transferred to Calochrom...

BackgroundThe incidence of total shoulder arthroplasty (TSA) continues to increase. Although researchers expect preoperative depression influence outcomes following primary hip and knee arthroplasty, there is a paucity data on this relationship after TSA. The purpose study was define the between diagnosis postoperative TSA.MethodsThis level III retrospective cohort study. We identified patients...

We conducted a prospective cohort study in a single tertiary hospital with the aim of assessing predictors of multidrug-resistant bacteremia in 307 cases of febrile neutropenia in adult patients with cancer. On multivariate analysis using stepwise logistic regression, age (P = .009), duration of neutropenia (P = .022), and presence of an indwelling central venous catheter (P = .022) were associ...