Aims. A complete census of obscured Active Galactic Nuclei (AGN) is necessary to reveal the history of the super massive black hole (SMBH) growth and galaxy evolution in the Universe given the complex feedback processes and the fact that much of this growth occurs in an obscured phase. In this context, hard X-ray surveys and dedicated follow-up observations represent a unique tool for selecting...


 CALHM1 controls Ca2+-dependent MEK/ERK/RSK/MSK signaling in 1
 neurons 2
 3
 Ute Dreses-Werringloer, Valérie Vingtdeux, Haitian Zhao, Pallavi Chandakkar, Peter 4
 Davies, Philippe Marambaud 5
 6
 Litwin-Zucker Research Center for the Study of Alzheimer’s Disease, The Feinstein Institute for 7
 Medical Research, Manhasset, New York, USA. Department of Pathology, Albert Einstein 8
 College of M...

There has been much recent interest in the use of the earliest-deadline-first (EDF) algorithm for scheduling soft real-time sporadic task systems on identical multiprocessors. In hard real-time systems, a significant disparity exists between EDF-based schemes and Pfair scheduling: on M processors, the worst-case schedulable utilization for all known EDF variants is approximately M/2, whereas it...

The large gain promised by the multi-input multi-output (MIMO) technology comes with a cost. In particular multiple analog radio frequency (RF) chains, which are expensive and power consuming, are required at both the transmitter and receiver sides. On the other hand, the antennas connecting to the RF chains are less expensive. Hence one engineering compromise is to implement more antennas than...

Background Despite multimodal management strategies, outcomes for patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN) remain poor. Immune checkpoint inhibitors have demonstrated promise as a neoadjuvant strategy to reduce relapse rates 1 ; however, immunosuppressive SCCHN tumour microenvironment (TME) has limited efficacy immunotherapy date. This ‘cold’ TME is ch...

The thermal unfolding curve for aa tropomyosin in which the two chains are cross-linked a t cysteine190 shows two striking features that distinguish it from that of its counterpart for non-cross-linked molecules: (1) a “pretransition” at 25-50 OC and (2) a shift in the principal transition to higher temperature, but with the same steepness. Previously, the pretransition was explained by postula...

Mangrove wetlands are economically and ecologically important ecosystems and accurate assessment of these wetlands with remote sensing can assist in their management and conservation. This study was conducted to evaluate airborne AISA hyperspectral imagery and image transformation and classification techniques for mapping black mangrove populations on the south Texas Gulf coast. AISA hyperspect...

Cellular retinaldehyde-binding protein (CRALBP) functions in the retinal pigment epithelium (RPE) as an acceptor of 11-cis-retinol in the isomerization step of the rod visual cycle and as a substrate carrier for 11-cisretinol dehydrogenase. Toward a better understanding of CRALBP function, the ligand binding cavity in human recombinant CRALBP (rCRALBP) was characterized by photoaffinity labelin...