The mechanisms of excessive sputum production are only partially understood. We speculated that a selective thromboxane (Tx) A2 synthetase inhibitor, OKY-046, now used in the treatment of asthma in Japan, could decrease excess sputum production in patients with chronic airways disease. To test this hypothesis, we carried out a double-blind, placebo-controlled study of the effects of OKY-046, ad...

Cyclooxygenase products are released by chronic airway inflammation. Our working hypothesis for the present study was that prostanoids augment airway cough sensitivity. The effects of a cyclooxygenase inhibitor, indomethacin (100 mg.day-1 for 4 days), and a thromboxane synthesis inhibitor, OKY-046 (400 mg.day-1 for 4 days), on cough response to inhaled capsaicin were examined in eight patients ...

X iv :1 50 6. 06 09 1v 1 [ nl in .A O ] 1 9 Ju n 20 15 Noise-induced synchronization in bidirectionally coupled Type-I neurons Nishant Malik, B. Ashok, and J. Balakrishnan Potsdam Institute for Climate Impact Research, Telegrafenberg, 14412 Potsdam, Germany. Advanced Centre for Research in High Energy Materials (ACRHEM), University of Hyderabad, Central University PO, Gachi Bowli, Hyderabad 500...

ABSTRACT We have undertaken a systematic study of FR I and II radio galaxies with the upgraded Giant Metrewave Radio Telescope (uGMRT) MeerKAT. The main goal is to explore whether unprecedented few μJy sensitivity reached in range 550–1712 MHz at resolution ∼4–7 arcsec reveals new features emission which might need us revise our current classification scheme for classical galaxies. In this pape...

Maurizio Bifulco1 and Anna Maria Malfitano2* 1Dipartimento di Farmacia, Università di Salerno, Fisciano, Salerno, Italy 2Dipartimento di Medicina e Chirurgia, Università di Salerno Facoltà di Medicina, Baronissi, Salerno *Corresponding author: Anna Maria Malfitano Dipartimento di Medicina e Chirurgia, Università di Salerno Facoltà di Medicina, Baronissi, Salerno, Tel: 0039-089-969742; E-mail: a...

The gamma-ray blazar PKS 1510−089 has a highly superluminal milli-arcsecond jet at a position angle (PA) of −28 and an arcsecond jet with an initial PA of 155. With a ∆PA of 177 between the arcsecond and milliarcsecond jets, PKS 1510−089 is perhaps the most highly misaligned radio jet ever observed and serves as a graphic example of projection effects in a highly beamed relativistic jet. Here w...

Neuronal acetylcholine nicotinic receptors (nAChRs) are targets for the development of novel treatments of brain diseases. However, adverse effects (for example, emesis or nausea) associated with high drug maximal exposures or C(max) at nAChRs often hinder the advancement of experimental compounds in clinical trials. Therefore, it is essential to explore the feasibility of maintaining exposures...

P. D. Sreekanth*, N. Geethanjali, P. D. Sreedevi, Shakeel Ahmed, N. Ravi Kumar and P. D. Kamala Jayanthi National Research Centre for Cashew, Puttur 574 202, India Sri Krishnadevaraya University, Anantapur 515 003, India National Geophysical Research Institute, Hyderabad 500 007, India Central Plantation Crops Research Institute, Kasaragod 671 124, India Indian Institute of Horticulture Researc...

C l i n M e d International Library Citation: Ali F, Kaushik GN, Carr ND, Hayes E, Plax KL (2016) Screening for Urethral, Rectal and Pharyngeal Gonorrhea & Chlamydia among Asymptomatic Male Adolescents and Young Men who have Sex with Men. J Fam Med Dis Prev 2:046 Received: August 20, 2016: Accepted: November 04, 2016: Published: November 08, 2016 Copyright: © 2016 Ali F, et al. This is an open-...