نتایج جستجو برای: 052

تعداد نتایج: 835  

2008
Marc Sauvage

As one of the lowest metallicity star forming galaxies, with a nucleus of several super star clusters, SBS0335-052E is the subject of substantial current study.

Journal: :Journal of the American College of Cardiology 2016

1999
Hannelore Brandt Ulf Dieckmann Gordon J. MacDonald

Fitness landscapes underlie the dynamics of evolutionary processes and are a key concept of evolutionary theory. Recent research on molecular folding and on evolutionary algorithms has demonstrated that such landscapes are also important for understanding problems of chemistry and of combinatorial optimization. In these cases free energy or cost functions are used instead of biological fitness ...

Journal: :The Journal of infectious diseases 2011
Susan H Eshleman Sarah E Hudelson Andrew D Redd Lei Wang Rachel Debes Ying Q Chen Craig A Martens Stacy M Ricklefs Ethan J Selig Stephen F Porcella Supriya Munshaw Stuart C Ray Estelle Piwowar-Manning Marybeth McCauley Mina C Hosseinipour Johnstone Kumwenda James G Hakim Suwat Chariyalertsak Guy de Bruyn Beatriz Grinsztejn Nagalingeswaran Kumarasamy Joseph Makhema Kenneth H Mayer Jose Pilotto Breno R Santos Thomas C Quinn Myron S Cohen James P Hughes

BACKGROUND The HIV Prevention Trials Network (HPTN) 052 trial demonstrated that early initiation of antiretroviral therapy (ART) reduces human immunodeficiency virus (HIV) transmission from HIV-infected adults (index participants) to their HIV-uninfected sexual partners. We analyzed HIV from 38 index-partner pairs and 80 unrelated index participants (controls) to assess the linkage of seroconve...

Journal: :International Journal of Infectious Diseases 2010

Journal: :Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2013
V Cambiano J O'Connor A N Phillips A Rodger R Lodwick A Pharris F Lampe F Nakagawa C Smith M J van de Laar

The aim of this review is to summarise the evidence on the population-level effect of antiretroviral therapy (ART) in preventing HIV infections, and to discuss potential implications in the European context of recommending starting ART when the CD4 count is above 350 cells/mm3. The ability of ART to reduce the risk of HIV transmission has been reported in observational studies and in a randomis...

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