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تعداد نتایج: 16827450 فیلتر نتایج به سال:
BACKGROUND Nivolumab, a monoclonal antibody of immune checkpoint programmed death 1 on T cells (PD-1), combined with ipilimumab, an immune checkpoint cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibitor, as combination therapy on the one hand and nivolumab as monotherapy on the other, have both demonstrated improved efficacy compared with ipilimumab alone in the CheckMate 067 study. H...
Producing electricity from wind is attractive because it provides a clean, low-maintenance power supply. However, wind resource is intermittent on various time scales, thus introducing variability in power output that is difficult for electric grid planning. In the following study, wind resource is characterized using metrics that highlight these intermittency issues, therefore identifying area...
This study was undertaken to evaluate the biological potency of two synthetic human growth hormone-releasing factors, hGRF (1-44)NH2 and hGRF (1-29)NH2, on growth hormone (GH) release in young dairy heifers (n = 10) and pigs (n = 10). In each species, the GH response to an iv injection (0, .067, .2, .6 and 1.8 nmol.kg-1 body weight) of each peptide was evaluated in a double 5 X 5 Latin square d...
One of the early concepts of space syntax, from the Social Logic of Space, is architecture seen as an interface. This is sometimes interpreted as on one hand a singular transition between ‘private’ and ‘public’, or more gradually as a transition from ‘public’ urban space towards more and more private space on the other. Methodologically, the latter tends to consist of analyses that incorporate ...
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