This research aimed to produce new 1-[(aryl)(3-amino-5-oxopyrazolidin-4-ylidene) methyl]-2-oxo-1,2-dihydroquinoline-3-carboxylic acid derivatives and check their anticancer effect against the breast cancer MCF-7 cell line. The 2-oxo-1,2-dihydroquinoline-3-carboxylic (4) compound was obtained by hydrolyzing ethyl 2-oxo-1,2-dihydroquinoline-3-carboxylate (2) with thiourea anhydrous potassium carb...

Z. Naturforsch. 56 b, 735-746 (2001); eingegangen am 16. Februar 2001 2,4-Dicyano Glutaconic Acid Diethyl Ester Anion, Cyano Bridges, Helix The anion of 2,4-dicyano glutaconic acid diethyl ester, [NCC(COOEt)CHC(COOEt)CN]_ ( I ), as an a,u;-dinitrile with a three atom spacer is a highly variable ligand capable of binding in a monodentate 77'-fashion, in a bidentate chelate fashion, and as a p 2-...

In this study, the physicochemical characteristics of pork loin, beef and chicken breast with various wet aging periods were analyzed to derive an appropriate period for each livestock. Pork loin stored at 4°C 0, 1, 2 weeks, was 2, 3, 4 proximate compositions, water holding capacity (WHC), cooking yield, shear force, volatile basic nitrogen (VBN), thiobarbituric acid reactive substances (TBARS)...

The solid–solid reactions of electron-donor compounds, such as: barbituric acid (1a), thiobarbituric acid (1b), 1,3-dimethyl barbituric acid (1c), phenol (1d) and resorcinol (1e) with diazotized o-nitroaniline (3), m-nitroaniline (4) and p-nitroaniline (5) catalyzed by p-toluenesulfonic acid (2) afford azo dyes by grinding in good yields. This new method totally avoids the use of inorganic acid...

1-Cyclopropylcyclopropanecarboxylic acid (2), which is accessible on a large scale (900 mmol) from 1-bromo-1-cyclopropylcyclopropane (1) in 64% yield (89% on a 12.4 mmol scale), has been subjected to a Curtius degradation employing the Weinstock protocol to furnish the N-Boc-protected (1-cyclopropyl)cyclopropylamine 3 (76%). Deprotection of 3 with hydrogen chloride in diethyl ether gave the (1-...

the synthesis and properties of new monoazo dyes derived from the diazonium salts of paminobenzoic acid, 3-trifluoromethyl aniline , 4-trifluoromethyl aniline are considered .theprepared compounds were characterized by uv-visible , ft-ir and h nmr spectroscopictechniques . the effect of varying solvent upon the absorption ability of p-amino benzoic acidcoupled with 4,4 —diethyl aniline , anilin...