Background: Biochanin A is an excellent dietary isoflavone that has the concomitant function of both medicine and foodstuff. The attenuation biochanin on blood-brain barrier (BBB) damage induced by cerebral ischemia-reperfusion remains unclear. Methods: C57BL/6 mice were subjected to 1 h middle artery occlusion (MCAO) followed 24 reperfusion. infarct volume brain was stained TTC, ...

Herpesvirus maturation requires translocation of glycoprotein B homologue from the endoplasmic reticulum to the inner nuclear membrane. Glycoprotein B of human cytomegalovirus was used in this context as a model protein. To identify a specific signal sequence within human cytomegalovirus glycoprotein B acting in a modular fashion, coding sequences were recombined with reporter proteins. Immunof...

The principal components of a variety of mucous secretions have been found to be glycoproteins, many of mol.wt. 500000 or more (Gottschalk, 1972). We have isolated the glycoprotein from pig colonic mucus and examined its structure in order to compare it with that of the well-characterized glycoprotein of the gastric mucus from the same species (Snary & Allen, 1971 ; Allen, 1977). Mucosal scrapi...

Tumor necrosis factor receptor (TNFR)-associated factors (TRAFs) are a family of intracellular signaling adaptors that associate with the cytoplasmic tails diverse range lymphocyte receptors, including members TNFR superfamily, Toll-like (TLR)/interleukin-1 (IL-1) and IL-6 major targets for therapeutic intervention inflammatory diseases. TRAF5 is one seven TRAF highly expressed by B- T-lymphocy...